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PRIMMO study protocol: a phase II study combining PD-1 blockade, radiation and immunomodulation to tackle cervical and uterine cancer
BACKGROUND: Immunotherapeutic approaches have revolutionized oncological practice but are less evaluated in gynecological malignancies. PD-1/PD-L1 blockade in gynecological cancers showed objective responses in 13–17% of patients. This could be due to immunosuppressive effects exerted by gynecologic...
Autores principales: | Tuyaerts, Sandra, Van Nuffel, An M. T., Naert, Eline, Van Dam, Peter A., Vuylsteke, Peter, De Caluwé, Alex, Aspeslagh, Sandrine, Dirix, Piet, Lippens, Lien, De Jaeghere, Emiel, Amant, Frédéric, Vandecasteele, Katrien, Denys, Hannelore |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6537207/ https://www.ncbi.nlm.nih.gov/pubmed/31138229 http://dx.doi.org/10.1186/s12885-019-5676-3 |
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