Cargando…

Mesenchymal stem cells overexpressing hepatocyte nuclear factor-4 alpha alleviate liver injury by modulating anti-inflammatory functions in mice

BACKGROUND: Mesenchymal stem cells (MSCs) can migrate to tissue injury sites where they can induce multipotential differentiation and anti-inflammation effects to treat tissue injury. When traditional therapeutic methods do not work, MSCs are considered to be one of the best candidates for cell ther...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ye, Zhenxiong, Lu, Wenfeng, Liang, Lei, Tang, Min, Wang, Yunfeng, Li, Zhen, Zeng, Heping, Wang, Aili, Lin, Moubin, Huang, Lei, Wang, Hui, Hu, Hai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6537220/ https://www.ncbi.nlm.nih.gov/pubmed/31133062 http://dx.doi.org/10.1186/s13287-019-1260-7

Ejemplares similares

Overexpression of apolipoprotein A-I alleviates endoplasmic reticulum stress in hepatocytes
por: Guo, Qing, et al.
Publicado: (2017)

Regulation of hepatic microRNA expression by hepatocyte nuclear factor 4 alpha
por: Lu, Hong, et al.
Publicado: (2017)

Establishment of human hair follicle mesenchymal stem cells with overexpressed human hepatocyte growth factor
por: Zhou, Dan, et al.
Publicado: (2017)

Hepatocyte Nuclear Factor 4 Alpha Is a Key Factor Related to Depression and Physiological Homeostasis in the Mouse Brain
por: Yamanishi, Kyosuke, et al.
Publicado: (2015)

The role of hepatocyte nuclear factor 4α (HNF4α) in tumorigenesis
por: Sang, Lei, et al.
Publicado: (2022)

Role of hepatocyte nuclear factor 4-alpha in gastrointestinal and liver diseases
por: Yeh, Matthew M, et al.
Publicado: (2019)

The hepatocyte-specifically expressed lnc-HSER alleviates hepatic fibrosis by inhibiting hepatocyte apoptosis and epithelial-mesenchymal transition
por: Zhang, Kun, et al.
Publicado: (2019)

Bone marrow mesenchymal stem cells overexpressing hepatocyte growth factor ameliorate hypoxic–ischemic brain damage in neonatal rats
por: Zeng, Wen, et al.
Publicado: (2021)

Serum transferrin as a biomarker of hepatocyte nuclear factor 4 alpha activity and hepatocyte function in liver diseases
por: Guldiken, Nurdan, et al.
Publicado: (2021)

Overexpression of MicroRNA-16 Alleviates Atherosclerosis by Inhibition of Inflammatory Pathways
por: Wang, Manman, et al.
Publicado: (2020)

TRIB1 is a positive regulator of hepatocyte nuclear factor 4-alpha
por: Soubeyrand, Sébastien, et al.
Publicado: (2017)

Hepatocyte nuclear factor 1 alpha influences pancreatic cancer growth and metastasis
por: Subramani, Ramadevi, et al.
Publicado: (2020)

Curcumin blunts epithelial-mesenchymal transition of hepatocytes to alleviate hepatic fibrosis through regulating oxidative stress and autophagy
por: Kong, Desong, et al.
Publicado: (2020)

Hepatocyte Nuclear Factor 4 Alpha Polymorphisms and the Metabolic Syndrome in French-Canadian Youth
por: Marcil, Valérie, et al.
Publicado: (2015)

The Role of Overexpressed Apolipoprotein AV in Insulin-Resistant Hepatocytes
por: Zhao, Wang, et al.
Publicado: (2020)

Expression profile analysis of the inflammatory response regulated by hepatocyte nuclear factor 4α
por: Wang, Zhongyan, et al.
Publicado: (2011)

The role of hepatocyte nuclear factor 4alpha in metastatic tumor formation of hepatocellular carcinoma and its close relationship with the mesenchymal–epithelial transition markers
por: Yao, Dianbo, et al.
Publicado: (2013)

Study of the expression levels of Hepatocyte nuclear factor 4 alpha and 3 beta in patients with different outcome of HBV infection
por: Chen, En-Qiang, et al.
Publicado: (2012)

Overexpression of Hepatocyte Cell Adhesion Molecule (hepaCAM) Inhibits the Proliferation, Migration, and Invasion in Colorectal Cancer Cells
por: Geng, Hai-tao, et al.
Publicado: (2017)

Pterostilbene Alleviates Cholestasis by Promoting SIRT1 Activity in Hepatocytes and Macrophages
por: Ma, Chuanrui, et al.
Publicado: (2021)

MicroRNA-133 overexpression promotes the therapeutic efficacy of mesenchymal stem cells on acute myocardial infarction
por: Chen, Yueqiu, et al.
Publicado: (2017)

Role of hepatocyte nuclear factor 4 alpha in cell proliferation and gemcitabine resistance in pancreatic adenocarcinoma
por: Sun, Qiqing, et al.
Publicado: (2019)

Mesenchymal stromal cells protect hepatocytes from lipotoxicity through alleviation of endoplasmic reticulum stress by restoring SERCA activity
por: Li, Linzhao, et al.
Publicado: (2021)

Systemic Overexpression of GDF5 in Adipocytes but Not Hepatocytes Alleviates High-Fat Diet-Induced Nonalcoholic Fatty Liver in Mice
por: Yang, Yan, et al.
Publicado: (2021)

Mechanism of Hepatocyte Apoptosis
por: Cao, Lei, et al.
Publicado: (2016)

ACE2 overexpressing mesenchymal stem cells alleviates COVID-19 lung injury by inhibiting pyroptosis
por: Wei, Jinhuan, et al.
Publicado: (2022)

The transcriptional activity of hepatocyte nuclear factor 4 alpha is inhibited via phosphorylation by ERK1/2
por: Vető, Borbála, et al.
Publicado: (2017)

Intrinsic hepatocyte dedifferentiation is accompanied by upregulation of mesenchymal markers, protein sialylation and core alpha 1,6 linked fucosylation
por: Mehta, Anand, et al.
Publicado: (2016)

Proteomic Analysis of Exosomes Secreted from Human Alpha-1 Antitrypsin Overexpressing Mesenchymal Stromal Cells
por: Wei, Hua, et al.
Publicado: (2021)

NAMPT overexpression alleviates alcohol-induced hepatic steatosis in mice
por: Xiong, Xiwen, et al.
Publicado: (2019)

Mesenchymal stem cells ameliorate lipid metabolism through reducing mitochondrial damage of hepatocytes in the treatment of post-hepatectomy liver failure
por: Wang, Jing-lin, et al.
Publicado: (2021)

Dexmedetomidine alleviates insulin resistance in hepatocytes by reducing endoplasmic reticulum stress
por: Liu, Fanfan, et al.
Publicado: (2019)

Hepatocyte Nuclear Factor 4 alpha 2 Messenger RNA Reprograms Liver‐Enriched Transcription Factors and Functional Proteins in End‐Stage Cirrhotic Human Hepatocytes
por: Tafaleng, Edgar N., et al.
Publicado: (2021)

Directed Differentiation of Adult Liver Derived Mesenchymal Like Stem Cells into Functional Hepatocytes
por: Luo, Xiaobei, et al.
Publicado: (2018)

Mutations in the coding regions of the hepatocyte nuclear factor 4 alpha in Iranian families with maturity onset diabetes of the young
por: Taghavi, Seyed Morteza, et al.
Publicado: (2009)

Global gene expression changes in liver following hepatocyte nuclear factor 4 alpha deletion in adult mice
por: Gunewardena, Sumedha, et al.
Publicado: (2015)

Microbiota regulate intestinal epithelial gene expression by suppressing the transcription factor Hepatocyte nuclear factor 4 alpha
por: Davison, James M., et al.
Publicado: (2017)

Mesenchymal stem cells alleviate aging in vitro and in vivo
por: Liu, Qun, et al.
Publicado: (2022)

Signalling pathways involved in the process of mesenchymal stem cells differentiating into hepatocytes
por: Ye, Jun‐Song, et al.
Publicado: (2015)

Overexpression Of Hepatocyte Nuclear Factor-1beta Predicting Poor Prognosis Is Associated With Biliary Phenotype In Patients With Hepatocellular Carcinoma
por: Yu, Dan-Dan, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_kc2shkkdcffjhdn98u0hpd8n4n