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New simple and quick method to analyze serum variant transthyretins: direct MALDI method for the screening of hereditary transthyretin amyloidosis

BACKGROUND: Hereditary transthyretin amyloidosis (ATTRv amyloidosis) is caused by a variant transthyretin (TTR), which is a serum protein secreted by the liver. Mass spectrometry (MS) is a useful tool that can detect variant TTRs in serum samples from patients with ATTRv amyloidosis. We previously r...

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Detalles Bibliográficos
Autores principales: Nomura, Toshiya, Ueda, Mitsuharu, Tasaki, Masayoshi, Misumi, Yohei, Masuda, Teruaki, Inoue, Yasuteru, Tsuda, Yukimoto, Okada, Masamitsu, Okazaki, Takahiro, Kanenawa, Kyosuke, Isoguchi, Aito, Nakamura, Makoto, Obayashi, Konen, Shinriki, Satoru, Matsui, Hirotaka, Yamashita, Taro, Ando, Yukio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6537225/
https://www.ncbi.nlm.nih.gov/pubmed/31133063
http://dx.doi.org/10.1186/s13023-019-1100-y

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