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Preoperative anxiety-induced glucocorticoid signaling reduces GABAergic markers in spinal cord and promotes postoperative hyperalgesia by affecting neuronal PAS domain protein 4

Preoperative anxiety is common in patients undergoing elective surgery and is closely related to postoperative hyperalgesia. In this study, a single prolonged stress model was used to induce preoperative anxiety-like behavior in rats 24 h before the surgery. We found that single prolonged stress exa...

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Detalles Bibliográficos
Autores principales:	Wu, Hao, Huang, Yulin, Tian, Xinyu, Zhang, Zuoxia, Zhang, Ying, Mao, Yanting, Wang, Chenchen, Yang, Shuai, Liu, Yue, Zhang, Wei, Ma, Zhengliang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6537253/ https://www.ncbi.nlm.nih.gov/pubmed/31041873 http://dx.doi.org/10.1177/1744806919850383

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