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Identification of variants and therapeutic epitopes in HPV-33/HPV-58 E6 and E7 in Southwest China

BACKGROUND: Human papillomavirus (HPV) E6 and E7 oncoproteins play a crucial role in HPV-related diseases, such as cervical cancer, and can be used as ideal targets for therapeutic vaccines. Human leukocyte antigen (HLA) participates in the immune response to block HPV infection and invasion by its...

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Detalles Bibliográficos
Autores principales: He, Jiaoyu, Yang, Yasi, Chen, Zuyi, Liu, Yang, Bao, Shanfei, Zhao, Yun, Ding, Xianping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6537359/
https://www.ncbi.nlm.nih.gov/pubmed/31138240
http://dx.doi.org/10.1186/s12985-019-1168-y