Cargando…

Identification of variants and therapeutic epitopes in HPV-33/HPV-58 E6 and E7 in Southwest China

BACKGROUND: Human papillomavirus (HPV) E6 and E7 oncoproteins play a crucial role in HPV-related diseases, such as cervical cancer, and can be used as ideal targets for therapeutic vaccines. Human leukocyte antigen (HLA) participates in the immune response to block HPV infection and invasion by its...

Descripción completa

Detalles Bibliográficos
Autores principales:	He, Jiaoyu, Yang, Yasi, Chen, Zuyi, Liu, Yang, Bao, Shanfei, Zhao, Yun, Ding, Xianping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6537359/ https://www.ncbi.nlm.nih.gov/pubmed/31138240 http://dx.doi.org/10.1186/s12985-019-1168-y

Ejemplares similares

E6 and E7 Gene Polymorphisms in Human Papillomavirus Types-58 and 33 Identified in Southwest China
por: Chen, Zuyi, et al.
Publicado: (2017)

Correction: E6 and E7 Gene Polymorphisms in Human Papillomavirus Types-58 and 33 Identified in Southwest China
por: Chen, Zuyi, et al.
Publicado: (2017)

L1 and L2 gene polymorphisms in HPV-58 and HPV-33: implications for vaccine design and diagnosis
por: Chen, Zuyi, et al.
Publicado: (2016)

The polymorphisms of LCR, E6, and E7 of HPV-58 isolates in Yunnan, Southwest China
por: Xi, Juemin, et al.
Publicado: (2018)

Phylogeny and polymorphism in the long control regions E6, E7, and L1 of HPV Type 56 in women from southwest China
por: Jing, Yaling, et al.
Publicado: (2018)

Evolution and Taxonomic Classification of Human Papillomavirus 16 (HPV16)-Related Variant Genomes: HPV31, HPV33, HPV35, HPV52, HPV58 and HPV67
por: Chen, Zigui, et al.
Publicado: (2011)

E7 Oncogene HPV58 Variants Detected in Northeast Brazil: Genetic and Functional Analysis
por: Chagas, Bárbara Simas, et al.
Publicado: (2023)

Genetic Variability in L1 and L2 Genes of HPV-16 and HPV-58 in Southwest China
por: Yue, Yaofei, et al.
Publicado: (2013)

HPV-16, HPV-58, and HPV-33 are the most carcinogenic HPV genotypes in Southwestern China and their viral loads are associated with severity of premalignant lesions in the cervix
por: Long, Wenbo, et al.
Publicado: (2018)

Phylogeny and polymorphism in the E6 and E7 of human papillomavirus: alpha-9 (HPV16, 31, 33, 52, 58), alpha-5 (HPV51), alpha-6 (HPV53, 66), alpha-7 (HPV18, 39, 59, 68) and alpha-10 (HPV6, 44) in women from Shanghai
por: Zhao, Junwei, et al.
Publicado: (2019)

HPV58 E7 Protein Expression Profile in Cervical Cancer and CIN with Immunohistochemistry
por: Zheng, Qiaoli, et al.
Publicado: (2021)

Production of Polyclonal Antibody to the HPV58 E7 Protein and Its Detection in Cervical Cancer
por: Zheng, Qiaoli, et al.
Publicado: (2016)

Sequence Variation Analysis of HPV-18 Isolates in Southwest China
por: Shen, Mengjie, et al.
Publicado: (2013)

Analysis of E2 gene integrity in HPV16 and HPV58 viruses isolated from women with cervical pathology
por: González-Losa, María del R, et al.
Publicado: (2016)

Identification of novel HLA-A*11:01-restricted HPV16 E6/E7 epitopes and T-cell receptors for HPV-related cancer immunotherapy
por: Xiong, Chengjie, et al.
Publicado: (2022)

Genetic variability of human papillomavirus type 39 based on E6, E7 and L1 genes in Southwest China
por: He, Jiaoyu, et al.
Publicado: (2021)

Fusion of CTLA-4 with HPV16 E7 and E6 Enhanced the Potency of Therapeutic HPV DNA Vaccine
por: Gan, Lili, et al.
Publicado: (2014)

Establishment of immunoassay for detecting HPV16 E6 and E7 RNA
por: Ding, Sen, et al.
Publicado: (2015)

Correction: Identification of novel HLA-A*11:01-restricted HPV16 E6/E7 epitopes and T-cell receptors for HPV-related cancer immunotherapy
Publicado: (2022)

Significance of HPV-58 Infection in Women Who Are HPV-Positive, Cytology-Negative and Living in a Country with a High Prevalence of HPV-58 Infection
por: Song, Joon Seon, et al.
Publicado: (2013)

Cervical carcinogenesis risk association of HPV33 E6 and E7 genetic variations in Taizhou, Southeast China
por: Yan, Zi-Yi, et al.
Publicado: (2023)

Implications of Persistent HPV52 and HPV58 Positivity for the Management of Cervical Lesions
por: Yi, Baozhu, et al.
Publicado: (2022)

Design, Immune Responses and Anti-Tumor Potential of an HPV16 E6E7 Multi-Epitope Vaccine
por: de Oliveira, Liliane Maria Fernandes, et al.
Publicado: (2015)

HPV genotype determination and E6/E7 mRNA detection for management of HPV positive women
por: Bruno, Maria Teresa, et al.
Publicado: (2018)

Identification of human MHC-I HPV18 E6/E7-specific CD8 + T cell epitopes and generation of an HPV18 E6/E7-expressing adenosquamous carcinoma in HLA-A2 transgenic mice
por: Peng, Shiwen, et al.
Publicado: (2022)

HPV16 E6/E7 -based mRNA vaccine is therapeutic in mice bearing aggressive HPV-positive lesions
por: Zhou, Kun, et al.
Publicado: (2023)

A DNA vaccine encoding mutated HPV58 mE6E7-Fc-GPI fusion antigen and GM-CSF and B7.1
por: Wang, He, et al.
Publicado: (2015)

A Non-oncogenic HPV 16 E6/E7 Vaccine Enhances Treatment of HPV Expressing Tumors
por: Wieking, Bryant G., et al.
Publicado: (2012)

The Expression of HPV E6/E7 mRNA In Situ Hybridization in HPV Typing-negative Cervical Cancer
por: Xu, Yating, et al.
Publicado: (2023)

Augmentation of cellular and humoral immune responses to HPV16 and HPV18 E6 and E7 antigens by VGX-3100
por: Morrow, Matthew P, et al.
Publicado: (2016)

Clinical analysis of HPV58-positive cervical cancer
por: Chen, Mengjie, et al.
Publicado: (2020)

E6 and E7 gene polymorphisms in human papillomavirus Type-6 identified in Southwest China
por: Chen, Zuyi, et al.
Publicado: (2019)

Association of cervical carcinogenesis risk with HPV16 E6 and E7 variants in the Taizhou area, China
por: Dai, Mei-Zhen, et al.
Publicado: (2021)

Prevalence of Human Papillomavirus Variants and Genetic Diversity in the L1 Gene and Long Control Region of HPV16, HPV31, and HPV58 Found in North-East Brazil
por: Gurgel, Ana Pavla Almeida Diniz, et al.
Publicado: (2015)

E6/E7 and E6(*) From HPV16 and HPV18 Upregulate IL-6 Expression Independently of p53 in Keratinocytes
por: Artaza-Irigaray, Cristina, et al.
Publicado: (2019)

Effects of HPV16 E6 protein on Daxx-induced apoptosis in C33A cells
por: Tang, Shuangyang, et al.
Publicado: (2020)

HPV16 E7 Nucleotide Variants Found in Cancer-Free Subjects Affect E7 Protein Expression and Transformation
por: Lou, Hong, et al.
Publicado: (2022)

HPV E2, E4, E5 drive alternative carcinogenic pathways in HPV positive cancers
por: Ren, Shuling, et al.
Publicado: (2020)

Diversity of cervicovaginal human papillomavirus (HPV) genotypes and naturally occurring E6/E7 DNA polymorphisms of HPV-16 in Ghana
por: Kaba, Gladys, et al.
Publicado: (2023)

HPV DNA methylation at the early promoter and E1/E2 integrity: A comparison between HPV16, HPV18 and HPV45 in cervical cancer
por: Amaro-Filho, Sérgio Menezes, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_ckda7cqev2pvsoop1bc94jtbsu