Crystal structure of a cytocidal protein from lamprey and its mechanism of action in the selective killing of cancer cells

BACKGROUND: In previous research, we found that lamprey immune protein (LIP) possessed cytocidal activity against tumor cells, but the mechanism of the selective recognition and killing of tumor cells by LIP was not identified. METHODS: Superresolution microscopy, crystallographic structural analysi...

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Detalles Bibliográficos
Autores principales: Pang, Yue, Gou, Meng, Yang, Kai, Lu, Jiali, Han, Yinglun, Teng, Hongming, Li, Changzhi, Wang, Haina, Liu, Caigang, Zhang, Kejia, Yang, Yongliang, Li, Qingwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6537362/
https://www.ncbi.nlm.nih.gov/pubmed/31133022
http://dx.doi.org/10.1186/s12964-019-0358-y

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