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Inhibition of ERK1/2 in cancer-associated pancreatic stellate cells suppresses cancer–stromal interaction and metastasis

BACKGROUND: Extracellular signal-regulated kinases (ERKs) have been related to multiple cancers, including breast cancer, hepatocellular cancer, lung cancer and colorectal cancer. ERK1/2 inhibitor can suppress growth of KRAS-mutant pancreatic tumors by targeting cancer cell. However, no studies have...

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Detalles Bibliográficos
Autores principales:	Yan, Zilong, Ohuchida, Kenoki, Fei, Shuang, Zheng, Biao, Guan, Weiyu, Feng, Haimin, Kibe, Shin, Ando, Yohei, Koikawa, Kazuhiro, Abe, Toshiya, Iwamoto, Chika, Shindo, Koji, Moriyama, Taiki, Nakata, Kohei, Miyasaka, Yoshihiro, Ohtsuka, Takao, Mizumoto, Kazuhiro, Hashizume, Makoto, Nakamura, Masafumi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6537367/ https://www.ncbi.nlm.nih.gov/pubmed/31133044 http://dx.doi.org/10.1186/s13046-019-1226-8

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