Capturing the differences between humoral immunity in the normal and tumor environments from repertoire-seq of B-cell receptors using supervised machine learning

BACKGROUND: The recent success of immunotherapy in treating tumors has attracted increasing interest in research related to the adaptive immune system in the tumor microenvironment. Recent advances in next-generation sequencing technology enabled the sequencing of whole T-cell receptors (TCRs) and B...

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Detalles Bibliográficos
Autores principales: Konishi, Hiroki, Komura, Daisuke, Katoh, Hiroto, Atsumi, Shinichiro, Koda, Hirotomo, Yamamoto, Asami, Seto, Yasuyuki, Fukayama, Masashi, Yamaguchi, Rui, Imoto, Seiya, Ishikawa, Shumpei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6537402/
https://www.ncbi.nlm.nih.gov/pubmed/31138102
http://dx.doi.org/10.1186/s12859-019-2853-y

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