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The role of fibroblast growth factor 1 and 2 on the pathological behavior of valve interstitial cells in a three-dimensional mechanically-conditioned model

BACKGROUND: More than five million Americans suffer from heart valve disease annually, a condition that worsens cardiac function and gradually leads to heart failure if appropriate treatment is not performed on time. Currently no medication can cure heart valve disease, leaving surgical intervention...

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Detalles Bibliográficos
Autores principales: Lam, Ngoc Thien, Tandon, Ishita, Balachandran, Kartik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6537403/
https://www.ncbi.nlm.nih.gov/pubmed/31149027
http://dx.doi.org/10.1186/s13036-019-0168-1