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An image-based assay to quantify changes in proliferation and viability upon drug treatment in 3D microenvironments

BACKGROUND: Every biological experiment requires a choice of throughput balanced against physiological relevance. Most primary drug screens neglect critical parameters such as microenvironmental conditions, cell-cell heterogeneity, and specific readouts of cell fate for the sake of throughput. METHO...

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Detalles Bibliográficos
Autores principales:	Murali, Vasanth S., Chang, Bo-Jui, Fiolka, Reto, Danuser, Gaudenz, Cobanoglu, Murat Can, Welf, Erik S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Technical Advance
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6537405/ https://www.ncbi.nlm.nih.gov/pubmed/31138163 http://dx.doi.org/10.1186/s12885-019-5694-1

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