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The small GTPase Rab5c is a key regulator of trafficking of the CD93/Multimerin-2/β1 integrin complex in endothelial cell adhesion and migration
BACKGROUND: In the endothelium, the single-pass membrane protein CD93, through its interaction with the extracellular matrix protein Multimerin-2, activates signaling pathways that are critical for vascular development and angiogenesis. Trafficking of adhesion molecules through endosomal compartment...
Autores principales: | Barbera, Stefano, Nardi, Federica, Elia, Ines, Realini, Giulia, Lugano, Roberta, Santucci, Annalisa, Tosi, Gian Marco, Dimberg, Anna, Galvagni, Federico, Orlandini, Maurizio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6537425/ https://www.ncbi.nlm.nih.gov/pubmed/31138217 http://dx.doi.org/10.1186/s12964-019-0375-x |
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