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The small GTPase Rab5c is a key regulator of trafficking of the CD93/Multimerin-2/β1 integrin complex in endothelial cell adhesion and migration

BACKGROUND: In the endothelium, the single-pass membrane protein CD93, through its interaction with the extracellular matrix protein Multimerin-2, activates signaling pathways that are critical for vascular development and angiogenesis. Trafficking of adhesion molecules through endosomal compartment...

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Detalles Bibliográficos
Autores principales: Barbera, Stefano, Nardi, Federica, Elia, Ines, Realini, Giulia, Lugano, Roberta, Santucci, Annalisa, Tosi, Gian Marco, Dimberg, Anna, Galvagni, Federico, Orlandini, Maurizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6537425/
https://www.ncbi.nlm.nih.gov/pubmed/31138217
http://dx.doi.org/10.1186/s12964-019-0375-x

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