Nutrient deprivation and lysosomal stress induce activation of TFEB in retinal pigment epithelial cells

BACKGROUND: Induction of lysosomal function and autophagy is regarded as an adaptive mechanism in response to cellular stress. The transcription factor EB (TFEB) has been identified as a master regulator of lysosomal function and autophagy. TFEB is a member of the microphthalmia family of bHLH-LZ tr...

Descripción completa

Detalles Bibliográficos
Autores principales: Pan, Hsuan-Yeh, Alamri, Abdulla H., Valapala, Mallika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6537441/
https://www.ncbi.nlm.nih.gov/pubmed/31160892
http://dx.doi.org/10.1186/s11658-019-0159-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6537441/
https://www.ncbi.nlm.nih.gov/pubmed/31160892
http://dx.doi.org/10.1186/s11658-019-0159-8

Ejemplares similares