Cargando…
Mosaic APP Gene Recombination in Alzheimer’s Disease—What’s Next?
A first example of somatic gene recombination (SGR) within the human brain was recently reported, involving the well-known Alzheimer’s disease (AD)-related gene amyloid precursor protein (APP). SGR was characterized by the creation of APP genomic complementary DNA (gencDNA) sequences that were ident...
Autores principales: | Lee, Ming-Hsiang, Chun, Jerold |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6537494/ https://www.ncbi.nlm.nih.gov/pubmed/31205422 http://dx.doi.org/10.1177/1179069519849669 |
Ejemplares similares
-
Mosaic Somatic Gene Recombination as a Potentially Unifying Hypothesis for Alzheimer’s Disease
por: Kaeser, Gwendolyn E., et al.
Publicado: (2020) -
Genomic mosaicism with increased amyloid precursor protein (APP) gene copy number in single neurons from sporadic Alzheimer's disease brains
por: Bushman, Diane M, et al.
Publicado: (2015) -
WhatsApp Doc?
por: Gould, Georgina, et al.
Publicado: (2016) -
The Future of Biobanking: What Is Next?
por: Caenazzo, Luciana, et al.
Publicado: (2020) -
An anti-amyloid therapy works for Alzheimer’s disease: why has it taken so long and what is next?
por: Hardy, John, et al.
Publicado: (2023)