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Pharmaceutical intervention after evaluation of the risk of ictus in elderly patients institutionalized with atrial fibrillation
OBJECTIVES: To evaluate the risk of having a stroke and the risk of bleeding in institutionalized patients with atrial fibrillation. Atrial fibrillation is a common cardiac arrhythmia associated with increased morbidity and mortality. It is necessary to develop pharmacotherapy plans to minimize the...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6537495/ https://www.ncbi.nlm.nih.gov/pubmed/31205686 http://dx.doi.org/10.1177/2048004019848273 |
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author | Pérez-Surio, Alberto Frutos Ortiz, Roberto Lozano Crespo, Alejandro Martínez |
author_facet | Pérez-Surio, Alberto Frutos Ortiz, Roberto Lozano Crespo, Alejandro Martínez |
author_sort | Pérez-Surio, Alberto Frutos |
collection | PubMed |
description | OBJECTIVES: To evaluate the risk of having a stroke and the risk of bleeding in institutionalized patients with atrial fibrillation. Atrial fibrillation is a common cardiac arrhythmia associated with increased morbidity and mortality. It is necessary to develop pharmacotherapy plans to minimize the risk. DESIGN: A prospective study. SETTING: Institutionalized patients. PARTICIPANTS: Inclusion criteria were: patients diagnosed with atrial fibrillation, with or without treatment for the prevention of stroke. MAIN OUTCOME MEASURES: The evaluation of the CHA2DS2-VASc criteria was performed. The risk of hemorrhage was assessed using the HAS-BLED scale, based on the risk factors associated with the probability of bleeding. RESULTS: We included 53 patients (86.4 ± 6.4 years, 30.2% men). Of these, 37 (69.8%) were correctly anticoagulated. Of the remaining, 5 patients (31.2%) did not have any type of anticoagulant or antiaggregant treatment and 11 (68.7%) were treated with antiaggregant alone. The pharmaceutical intervention was performed in patients who did not meet stroke criteria. Of the untreated patients: two died before the intervention, two were recommended to be referred to cardiology and in one there was no intervention because of very advanced age. In the antiaggregant patients, it was decided not to modify the treatment. The reasons were: high risk of bleeding, very advanced age, advanced dementia or terminal illness, moderate risk of stroke, and clotting factor deficiency. CONCLUSIONS: The risk of stroke in elderly patients with atrial fibrillation is high, so it is important to control the risk factors. |
format | Online Article Text |
id | pubmed-6537495 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-65374952019-06-14 Pharmaceutical intervention after evaluation of the risk of ictus in elderly patients institutionalized with atrial fibrillation Pérez-Surio, Alberto Frutos Ortiz, Roberto Lozano Crespo, Alejandro Martínez JRSM Cardiovasc Dis Research Paper OBJECTIVES: To evaluate the risk of having a stroke and the risk of bleeding in institutionalized patients with atrial fibrillation. Atrial fibrillation is a common cardiac arrhythmia associated with increased morbidity and mortality. It is necessary to develop pharmacotherapy plans to minimize the risk. DESIGN: A prospective study. SETTING: Institutionalized patients. PARTICIPANTS: Inclusion criteria were: patients diagnosed with atrial fibrillation, with or without treatment for the prevention of stroke. MAIN OUTCOME MEASURES: The evaluation of the CHA2DS2-VASc criteria was performed. The risk of hemorrhage was assessed using the HAS-BLED scale, based on the risk factors associated with the probability of bleeding. RESULTS: We included 53 patients (86.4 ± 6.4 years, 30.2% men). Of these, 37 (69.8%) were correctly anticoagulated. Of the remaining, 5 patients (31.2%) did not have any type of anticoagulant or antiaggregant treatment and 11 (68.7%) were treated with antiaggregant alone. The pharmaceutical intervention was performed in patients who did not meet stroke criteria. Of the untreated patients: two died before the intervention, two were recommended to be referred to cardiology and in one there was no intervention because of very advanced age. In the antiaggregant patients, it was decided not to modify the treatment. The reasons were: high risk of bleeding, very advanced age, advanced dementia or terminal illness, moderate risk of stroke, and clotting factor deficiency. CONCLUSIONS: The risk of stroke in elderly patients with atrial fibrillation is high, so it is important to control the risk factors. SAGE Publications 2019-05-24 /pmc/articles/PMC6537495/ /pubmed/31205686 http://dx.doi.org/10.1177/2048004019848273 Text en © The Author(s) 2019 http://creativecommons.org/licenses/by-nc/4.0/ Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Research Paper Pérez-Surio, Alberto Frutos Ortiz, Roberto Lozano Crespo, Alejandro Martínez Pharmaceutical intervention after evaluation of the risk of ictus in elderly patients institutionalized with atrial fibrillation |
title | Pharmaceutical intervention after evaluation of the risk of ictus in elderly patients institutionalized with atrial fibrillation |
title_full | Pharmaceutical intervention after evaluation of the risk of ictus in elderly patients institutionalized with atrial fibrillation |
title_fullStr | Pharmaceutical intervention after evaluation of the risk of ictus in elderly patients institutionalized with atrial fibrillation |
title_full_unstemmed | Pharmaceutical intervention after evaluation of the risk of ictus in elderly patients institutionalized with atrial fibrillation |
title_short | Pharmaceutical intervention after evaluation of the risk of ictus in elderly patients institutionalized with atrial fibrillation |
title_sort | pharmaceutical intervention after evaluation of the risk of ictus in elderly patients institutionalized with atrial fibrillation |
topic | Research Paper |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6537495/ https://www.ncbi.nlm.nih.gov/pubmed/31205686 http://dx.doi.org/10.1177/2048004019848273 |
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