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Applying Beers Criteria for Elderly Patients to Assess Rational Drug Use at a University Hospital in Northern Cyprus
BACKGROUND: Several regulations for potentially inappropriate medications (PIMs) have been published specifically for elderly patients to rationalize drug use in such vulnerable communities. OBJECTIVES: To determine the proportion and characteristics of PIMs in patients receiving one or more drugs a...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6537642/ https://www.ncbi.nlm.nih.gov/pubmed/31148889 http://dx.doi.org/10.4103/jpbs.JPBS_208_18 |
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author | Khamis, Sarah Abdi, Abdikarim Mohamed Uzan, Ali Basgut, Bilgen |
author_facet | Khamis, Sarah Abdi, Abdikarim Mohamed Uzan, Ali Basgut, Bilgen |
author_sort | Khamis, Sarah |
collection | PubMed |
description | BACKGROUND: Several regulations for potentially inappropriate medications (PIMs) have been published specifically for elderly patients to rationalize drug use in such vulnerable communities. OBJECTIVES: To determine the proportion and characteristics of PIMs in patients receiving one or more drugs according to Beers Criteria 2015. MATERIALS AND METHODS: A cross-sectional prospective analysis of 451 inpatients admitted between September 25 and October 25, 2016, was conducted in Near East University Hospital, Northern Cyprus. Data were extracted from the patient medical records using special forms. RESULTS: A total of 119 elderly patients were identified (26.4%) and evaluated, of which 107 were eligible and 12 were excluded. Of the 1039 prescribed medicines, 16.9% were PIMs during hospitalization, whereas 12% were at discharge. The most prevalent PIM group during hospitalization was identified as the “medications to be avoided in older adults” (48.8%), whereas it also formed 52% of medications prescribed at discharge. PIMs of the class “drugs used with caution” formed 19.4% of prescribed medicine during hospitalization and 18.4% on discharge. The prevalence of polypharmacy was 79.4%, mainly identified as unpreventable polypharmacy of elders. CONCLUSION: A significantly higher prevalence of PIMs was observed in hospitalized patients than those discharged, with high prevalence of polypharmacy. These results necessitate a nationwide assessment, and responsible bodies who adopt strategies should act to reduce or overcome the aforementioned high prevalence in Northern Cyprus. |
format | Online Article Text |
id | pubmed-6537642 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-65376422019-05-30 Applying Beers Criteria for Elderly Patients to Assess Rational Drug Use at a University Hospital in Northern Cyprus Khamis, Sarah Abdi, Abdikarim Mohamed Uzan, Ali Basgut, Bilgen J Pharm Bioallied Sci Original Article BACKGROUND: Several regulations for potentially inappropriate medications (PIMs) have been published specifically for elderly patients to rationalize drug use in such vulnerable communities. OBJECTIVES: To determine the proportion and characteristics of PIMs in patients receiving one or more drugs according to Beers Criteria 2015. MATERIALS AND METHODS: A cross-sectional prospective analysis of 451 inpatients admitted between September 25 and October 25, 2016, was conducted in Near East University Hospital, Northern Cyprus. Data were extracted from the patient medical records using special forms. RESULTS: A total of 119 elderly patients were identified (26.4%) and evaluated, of which 107 were eligible and 12 were excluded. Of the 1039 prescribed medicines, 16.9% were PIMs during hospitalization, whereas 12% were at discharge. The most prevalent PIM group during hospitalization was identified as the “medications to be avoided in older adults” (48.8%), whereas it also formed 52% of medications prescribed at discharge. PIMs of the class “drugs used with caution” formed 19.4% of prescribed medicine during hospitalization and 18.4% on discharge. The prevalence of polypharmacy was 79.4%, mainly identified as unpreventable polypharmacy of elders. CONCLUSION: A significantly higher prevalence of PIMs was observed in hospitalized patients than those discharged, with high prevalence of polypharmacy. These results necessitate a nationwide assessment, and responsible bodies who adopt strategies should act to reduce or overcome the aforementioned high prevalence in Northern Cyprus. Wolters Kluwer - Medknow 2019 /pmc/articles/PMC6537642/ /pubmed/31148889 http://dx.doi.org/10.4103/jpbs.JPBS_208_18 Text en Copyright: © 2019 Journal of Pharmacy and Bioallied Sciences http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Original Article Khamis, Sarah Abdi, Abdikarim Mohamed Uzan, Ali Basgut, Bilgen Applying Beers Criteria for Elderly Patients to Assess Rational Drug Use at a University Hospital in Northern Cyprus |
title | Applying Beers Criteria for Elderly Patients to Assess Rational Drug Use at a University Hospital in Northern Cyprus |
title_full | Applying Beers Criteria for Elderly Patients to Assess Rational Drug Use at a University Hospital in Northern Cyprus |
title_fullStr | Applying Beers Criteria for Elderly Patients to Assess Rational Drug Use at a University Hospital in Northern Cyprus |
title_full_unstemmed | Applying Beers Criteria for Elderly Patients to Assess Rational Drug Use at a University Hospital in Northern Cyprus |
title_short | Applying Beers Criteria for Elderly Patients to Assess Rational Drug Use at a University Hospital in Northern Cyprus |
title_sort | applying beers criteria for elderly patients to assess rational drug use at a university hospital in northern cyprus |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6537642/ https://www.ncbi.nlm.nih.gov/pubmed/31148889 http://dx.doi.org/10.4103/jpbs.JPBS_208_18 |
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