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Real-Time Temporal Dynamics of Bicistronic Expression Mediated by Internal Ribosome Entry Site and 2A Cleaving Sequence

Multicistronic elements, such as the internal ribosome entry site (IRES) and 2A-like cleavage sequence, serve crucial roles in the eukaryotic ectopic expression of exogenous genes. For utilization of multicistronic elements, the cleavage efficiency and order of elements in multicistronic vectors hav...

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Detalles Bibliográficos
Autores principales: Lee, Soomin, Kim, Jeong-Ah, Kim, Hee-Dae, Chung, Sooyoung, Kim, Kyungjin, Choe, Han Kyoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6537651/
https://www.ncbi.nlm.nih.gov/pubmed/31085809
http://dx.doi.org/10.14348/molcells.2019.2427