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Radon Therapy for Autoimmune Diseases Pemphigus and Diabetes: 2 Case Reports
We report on the application of radon therapy to relieve the suffering of 2 patients with autoimmune diseases, one with pemphigus with an old myocardial infarction and diabetes mellitus and the other with type I diabetes. We include a lengthy discussion of the biological mechanisms that we believe p...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6537674/ https://www.ncbi.nlm.nih.gov/pubmed/31191185 http://dx.doi.org/10.1177/1559325819850984 |
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author | Kojima, Shuji Cuttler, Jerry M. Shimura, Noriko Koga, Hironobu Murata, Akihisa Kawashima, Akira |
author_facet | Kojima, Shuji Cuttler, Jerry M. Shimura, Noriko Koga, Hironobu Murata, Akihisa Kawashima, Akira |
author_sort | Kojima, Shuji |
collection | PubMed |
description | We report on the application of radon therapy to relieve the suffering of 2 patients with autoimmune diseases, one with pemphigus with an old myocardial infarction and diabetes mellitus and the other with type I diabetes. We include a lengthy discussion of the biological mechanisms that we believe produced the observed benefits. During the 6 to 9 months of the treatments, the marker values decreased to the upper limit of their normal ranges and the symptoms of the diseases were alleviated. Disorders of Th1/Th2 balance are implicated in the onset of many diseases, including autoimmune diseases. Our decision to give radon ((222)Rn) therapy to these patients was based on the results of 2 similar case reports and our earlier mouse experiments, which indicated that low doses of radiation induce regulatory T cells. Regulatory T cells regulate the T helper 1 cell and the T helper 2 cell balance. There are more than 80 different autoimmune diseases that are treated with anti-inflammatory agents or immune-suppressing drugs because the exact causes of these diseases and the cures are unknown. These and other case reports indicate that proper radon therapy is an effective treatment. We urge physicians to consider radon as a standard therapy for refractory autoimmune diseases. |
format | Online Article Text |
id | pubmed-6537674 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-65376742019-06-12 Radon Therapy for Autoimmune Diseases Pemphigus and Diabetes: 2 Case Reports Kojima, Shuji Cuttler, Jerry M. Shimura, Noriko Koga, Hironobu Murata, Akihisa Kawashima, Akira Dose Response Clinical Case We report on the application of radon therapy to relieve the suffering of 2 patients with autoimmune diseases, one with pemphigus with an old myocardial infarction and diabetes mellitus and the other with type I diabetes. We include a lengthy discussion of the biological mechanisms that we believe produced the observed benefits. During the 6 to 9 months of the treatments, the marker values decreased to the upper limit of their normal ranges and the symptoms of the diseases were alleviated. Disorders of Th1/Th2 balance are implicated in the onset of many diseases, including autoimmune diseases. Our decision to give radon ((222)Rn) therapy to these patients was based on the results of 2 similar case reports and our earlier mouse experiments, which indicated that low doses of radiation induce regulatory T cells. Regulatory T cells regulate the T helper 1 cell and the T helper 2 cell balance. There are more than 80 different autoimmune diseases that are treated with anti-inflammatory agents or immune-suppressing drugs because the exact causes of these diseases and the cures are unknown. These and other case reports indicate that proper radon therapy is an effective treatment. We urge physicians to consider radon as a standard therapy for refractory autoimmune diseases. SAGE Publications 2019-05-19 /pmc/articles/PMC6537674/ /pubmed/31191185 http://dx.doi.org/10.1177/1559325819850984 Text en © The Author(s) 2019 http://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Clinical Case Kojima, Shuji Cuttler, Jerry M. Shimura, Noriko Koga, Hironobu Murata, Akihisa Kawashima, Akira Radon Therapy for Autoimmune Diseases Pemphigus and Diabetes: 2 Case Reports |
title | Radon Therapy for Autoimmune Diseases Pemphigus and Diabetes: 2 Case Reports |
title_full | Radon Therapy for Autoimmune Diseases Pemphigus and Diabetes: 2 Case Reports |
title_fullStr | Radon Therapy for Autoimmune Diseases Pemphigus and Diabetes: 2 Case Reports |
title_full_unstemmed | Radon Therapy for Autoimmune Diseases Pemphigus and Diabetes: 2 Case Reports |
title_short | Radon Therapy for Autoimmune Diseases Pemphigus and Diabetes: 2 Case Reports |
title_sort | radon therapy for autoimmune diseases pemphigus and diabetes: 2 case reports |
topic | Clinical Case |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6537674/ https://www.ncbi.nlm.nih.gov/pubmed/31191185 http://dx.doi.org/10.1177/1559325819850984 |
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