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Radon Therapy for Autoimmune Diseases Pemphigus and Diabetes: 2 Case Reports

We report on the application of radon therapy to relieve the suffering of 2 patients with autoimmune diseases, one with pemphigus with an old myocardial infarction and diabetes mellitus and the other with type I diabetes. We include a lengthy discussion of the biological mechanisms that we believe p...

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Autores principales: Kojima, Shuji, Cuttler, Jerry M., Shimura, Noriko, Koga, Hironobu, Murata, Akihisa, Kawashima, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6537674/
https://www.ncbi.nlm.nih.gov/pubmed/31191185
http://dx.doi.org/10.1177/1559325819850984
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author Kojima, Shuji
Cuttler, Jerry M.
Shimura, Noriko
Koga, Hironobu
Murata, Akihisa
Kawashima, Akira
author_facet Kojima, Shuji
Cuttler, Jerry M.
Shimura, Noriko
Koga, Hironobu
Murata, Akihisa
Kawashima, Akira
author_sort Kojima, Shuji
collection PubMed
description We report on the application of radon therapy to relieve the suffering of 2 patients with autoimmune diseases, one with pemphigus with an old myocardial infarction and diabetes mellitus and the other with type I diabetes. We include a lengthy discussion of the biological mechanisms that we believe produced the observed benefits. During the 6 to 9 months of the treatments, the marker values decreased to the upper limit of their normal ranges and the symptoms of the diseases were alleviated. Disorders of Th1/Th2 balance are implicated in the onset of many diseases, including autoimmune diseases. Our decision to give radon ((222)Rn) therapy to these patients was based on the results of 2 similar case reports and our earlier mouse experiments, which indicated that low doses of radiation induce regulatory T cells. Regulatory T cells regulate the T helper 1 cell and the T helper 2 cell balance. There are more than 80 different autoimmune diseases that are treated with anti-inflammatory agents or immune-suppressing drugs because the exact causes of these diseases and the cures are unknown. These and other case reports indicate that proper radon therapy is an effective treatment. We urge physicians to consider radon as a standard therapy for refractory autoimmune diseases.
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spelling pubmed-65376742019-06-12 Radon Therapy for Autoimmune Diseases Pemphigus and Diabetes: 2 Case Reports Kojima, Shuji Cuttler, Jerry M. Shimura, Noriko Koga, Hironobu Murata, Akihisa Kawashima, Akira Dose Response Clinical Case We report on the application of radon therapy to relieve the suffering of 2 patients with autoimmune diseases, one with pemphigus with an old myocardial infarction and diabetes mellitus and the other with type I diabetes. We include a lengthy discussion of the biological mechanisms that we believe produced the observed benefits. During the 6 to 9 months of the treatments, the marker values decreased to the upper limit of their normal ranges and the symptoms of the diseases were alleviated. Disorders of Th1/Th2 balance are implicated in the onset of many diseases, including autoimmune diseases. Our decision to give radon ((222)Rn) therapy to these patients was based on the results of 2 similar case reports and our earlier mouse experiments, which indicated that low doses of radiation induce regulatory T cells. Regulatory T cells regulate the T helper 1 cell and the T helper 2 cell balance. There are more than 80 different autoimmune diseases that are treated with anti-inflammatory agents or immune-suppressing drugs because the exact causes of these diseases and the cures are unknown. These and other case reports indicate that proper radon therapy is an effective treatment. We urge physicians to consider radon as a standard therapy for refractory autoimmune diseases. SAGE Publications 2019-05-19 /pmc/articles/PMC6537674/ /pubmed/31191185 http://dx.doi.org/10.1177/1559325819850984 Text en © The Author(s) 2019 http://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Clinical Case
Kojima, Shuji
Cuttler, Jerry M.
Shimura, Noriko
Koga, Hironobu
Murata, Akihisa
Kawashima, Akira
Radon Therapy for Autoimmune Diseases Pemphigus and Diabetes: 2 Case Reports
title Radon Therapy for Autoimmune Diseases Pemphigus and Diabetes: 2 Case Reports
title_full Radon Therapy for Autoimmune Diseases Pemphigus and Diabetes: 2 Case Reports
title_fullStr Radon Therapy for Autoimmune Diseases Pemphigus and Diabetes: 2 Case Reports
title_full_unstemmed Radon Therapy for Autoimmune Diseases Pemphigus and Diabetes: 2 Case Reports
title_short Radon Therapy for Autoimmune Diseases Pemphigus and Diabetes: 2 Case Reports
title_sort radon therapy for autoimmune diseases pemphigus and diabetes: 2 case reports
topic Clinical Case
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6537674/
https://www.ncbi.nlm.nih.gov/pubmed/31191185
http://dx.doi.org/10.1177/1559325819850984
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