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Pharmacodynamic study of radium-223 in men with bone metastatic castration resistant prostate cancer
BACKGROUND: Radium-223 is a targeted alpha-particle therapy that improves survival in men with metastatic castration resistant prostate cancer (mCRPC), particularly in men with elevated serum levels of bone alkaline phosphatase (B-ALP). We hypothesized that osteomimicry, a form of epithelial plastic...
Autores principales: | Armstrong, Andrew J., Gupta, Santosh, Healy, Patrick, Kemeny, Gabor, Leith, Beth, Zalutsky, Michael R., Spritzer, Charles, Davies, Catrin, Rothwell, Colin, Ware, Kathryn, Somarelli, Jason A., Wood, Kris, Ribar, Thomas, Giannakakou, Paraskevi, Zhang, Jiaren, Gerber, Drew, Anand, Monika, Foo, Wen-Chi, Halabi, Susan, Gregory, Simon G., George, Daniel J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538141/ https://www.ncbi.nlm.nih.gov/pubmed/31136607 http://dx.doi.org/10.1371/journal.pone.0216934 |
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