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Quantitative cell-based model predicts mechanical stress response of growing tumor spheroids over various growth conditions and cell lines

Model simulations indicate that the response of growing cell populations on mechanical stress follows the same functional relationship and is predictable over different cell lines and growth conditions despite experimental response curves look largely different. We develop a hybrid model strategy in...

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Detalles Bibliográficos
Autores principales: Van Liedekerke, Paul, Neitsch, Johannes, Johann, Tim, Alessandri, Kevin, Nassoy, Pierre, Drasdo, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538187/
https://www.ncbi.nlm.nih.gov/pubmed/30849070
http://dx.doi.org/10.1371/journal.pcbi.1006273

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