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Quantitative cell-based model predicts mechanical stress response of growing tumor spheroids over various growth conditions and cell lines
Model simulations indicate that the response of growing cell populations on mechanical stress follows the same functional relationship and is predictable over different cell lines and growth conditions despite experimental response curves look largely different. We develop a hybrid model strategy in...
Autores principales: | Van Liedekerke, Paul, Neitsch, Johannes, Johann, Tim, Alessandri, Kevin, Nassoy, Pierre, Drasdo, Dirk |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538187/ https://www.ncbi.nlm.nih.gov/pubmed/30849070 http://dx.doi.org/10.1371/journal.pcbi.1006273 |
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