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Th1 Biased Progressive Autoimmunity in Aged Aire-Deficient Mice Accelerated Thymic Epithelial Cell Senescence
Although autoimmune diseases, such as rheumatoid arthritis and systemic lupus erythematosus, are frequently associated with premature aging of the thymus, a direct link is missing between autoimmunity and thymic atrophy. Here we monitored the progression of thymic involution in Aire-deficient mice,...
Autores principales: | Zhang, Jie, Wang, Yuqing, Aili, Abudureyimujiang, Sun, Xiuyuan, Pang, Xuewen, Ge, Qing, Zhang, Yu, Jin, Rong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
JKL International LLC
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538216/ https://www.ncbi.nlm.nih.gov/pubmed/31164995 http://dx.doi.org/10.14336/AD.2018.0608 |
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