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Composite biomaterial repair strategy to restore biomechanical function and reduce herniation risk in an ex vivo large animal model of intervertebral disc herniation with varying injury severity
Back pain commonly arises from intervertebral disc (IVD) damage including annulus fibrosus (AF) defects and nucleus pulposus (NP) loss. Poor IVD healing motivates developing tissue engineering repair strategies. This study evaluated a composite injectable IVD biomaterial repair strategy using carbox...
Autores principales: | Hom, Warren W., Tschopp, Melanie, Lin, Huizi A., Nasser, Philip, Laudier, Damien M., Hecht, Andrew C., Nicoll, Steven B., Iatridis, James C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538241/ https://www.ncbi.nlm.nih.gov/pubmed/31136604 http://dx.doi.org/10.1371/journal.pone.0217357 |
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