Regulatory switch at the cytoplasmic interface controls TRPV channel gating

Temperature-sensitive transient receptor potential vanilloid (thermoTRPV) channels are activated by ligands and heat, and are involved in various physiological processes. ThermoTRPV channels possess a large cytoplasmic ring consisting of N-terminal ankyrin repeat domains (ARD) and C-terminal domains...

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Detalles Bibliográficos
Autores principales: Zubcevic, Lejla, Borschel, William F, Hsu, Allen L, Borgnia, Mario J, Lee, Seok-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Structural Biology and Molecular Biophysics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538378/
https://www.ncbi.nlm.nih.gov/pubmed/31070581
http://dx.doi.org/10.7554/eLife.47746

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538378/
https://www.ncbi.nlm.nih.gov/pubmed/31070581
http://dx.doi.org/10.7554/eLife.47746

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