The major secreted protein of the whipworm parasite tethers to matrix and inhibits interleukin-13 function

Infection by soil transmitted parasitic helminths, such as Trichuris spp, are ubiquitous in humans and animals but the mechanisms determining persistence of chronic infections are poorly understood. Here we show that p43, the single most abundant protein in T. muris excretions/secretions, is non-imm...

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Detalles Bibliográficos
Autores principales: Bancroft, Allison J., Levy, Colin W., Jowitt, Thomas A., Hayes, Kelly S., Thompson, Seona, Mckenzie, Edward A., Ball, Matthew D., Dubaissi, Eamon, France, Aidan P., Bellina, Bruno, Sharpe, Catherine, Mironov, Aleksandr, Brown, Sheila L., Cook, Peter C., S. MacDonald, Andrew, Thornton, David J., Grencis, Richard K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538607/
https://www.ncbi.nlm.nih.gov/pubmed/31138806
http://dx.doi.org/10.1038/s41467-019-09996-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538607/
https://www.ncbi.nlm.nih.gov/pubmed/31138806
http://dx.doi.org/10.1038/s41467-019-09996-z

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