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Endophilin-A2 dependent VEGFR2 endocytosis promotes sprouting angiogenesis
Endothelial cell migration, proliferation and survival are triggered by VEGF-A activation of VEGFR2. However, how these cell behaviors are regulated individually is still unknown. Here we identify Endophilin-A2 (ENDOA2), a BAR-domain protein that orchestrates CLATHRIN-independent internalization, as...
Autores principales: | Genet, Gael, Boyé, Kevin, Mathivet, Thomas, Ola, Roxana, Zhang, Feng, Dubrac, Alexandre, Li, Jinyu, Genet, Nafiisha, Henrique Geraldo, Luiz, Benedetti, Lorena, Künzel, Steffen, Pibouin-Fragner, Laurence, Thomas, Jean-Leon, Eichmann, Anne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538628/ https://www.ncbi.nlm.nih.gov/pubmed/31138815 http://dx.doi.org/10.1038/s41467-019-10359-x |
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