ZNF479 downregulates metallothionein-1 expression by regulating ASH2L and DNMT1 in hepatocellular carcinoma

Decreased expression of metallothionein-1 (MT-1) is associated with a poor prognosis in hepatocellular carcinoma (HCC). Here, we found that MT-1 expression was suppressed by 14-3-3ε, and MT-1 overexpression abolished 14-3-3ε-induced cell proliferation and tumor growth. We identified that 14-3-3ε ind...

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Detalles Bibliográficos
Autores principales: Wu, Yi-Ju, Ko, Bor-Sheng, Liang, Shu-Man, Lu, Yi-Jhu, Jan, Yee-Jee, Jiang, Shih-Sheng, Shyue, Song-Kun, Chen, Linyi, Liou, Jun-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538656/
https://www.ncbi.nlm.nih.gov/pubmed/31138789
http://dx.doi.org/10.1038/s41419-019-1651-9

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