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Delineating the role of eIF2α in retinal degeneration
Activation of the unfolded protein response has been detected in various animal models of retinal degeneration. The PERK branch converges on eIF2α to regulate protein synthesis. We previously reported that diseased retinas produce less protein as they degenerate. We also proposed that the majority o...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538684/ https://www.ncbi.nlm.nih.gov/pubmed/31138784 http://dx.doi.org/10.1038/s41419-019-1641-y |