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Progress in the identification of gene mutations involved in multiple myeloma

Sequencing studies have been used to determine a spectrum of multiple myeloma (MM) mutations. Mutation of certain genes, including KRAS, NRAS, TP53, FAM46C, DIS3 and BRAF, have a high recurrence rate and may play important roles in the pathogenesis, progression and prognosis of MM. Mutations in DIS3...

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Detalles Bibliográficos
Autores principales: Hu, Ying, Chen, Wenming, Wang, Jingbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538831/
https://www.ncbi.nlm.nih.gov/pubmed/31213829
http://dx.doi.org/10.2147/OTT.S205922