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Proprotein Convertase Subtilisin/Kexin Type 9, Brain Cholesterol Homeostasis and Potential Implication for Alzheimer’s Disease

Alzheimer’s disease (AD) has been associated with dysregulation of brain cholesterol homeostasis. Proprotein convertase subtilisin/kexin type 9 (PCSK9), beyond the known role in the regulation of plasma low-density lipoprotein cholesterol, was first identified in the brain with a potential involveme...

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Detalles Bibliográficos
Autores principales: Adorni, Maria Pia, Ruscica, Massimiliano, Ferri, Nicola, Bernini, Franco, Zimetti, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538876/
https://www.ncbi.nlm.nih.gov/pubmed/31178716
http://dx.doi.org/10.3389/fnagi.2019.00120