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RA-XII Suppresses the Development and Growth of Liver Cancer by Inhibition of Lipogenesis via SCAP-dependent SREBP Supression
Lipogenesis plays a critical role in the growth and metastasis of tumors, which is becoming an attractive target for anti-tumor drugs. RA-XII, one of the cyclopeptide glycosides isolated from Rubia yunnanensis, exerts anti-tumor effects on liver cancer. However, the underlying mechanisms are not cle...
Autores principales: | Guo, Di, Wang, Yurong, Wang, Jing, Song, Lihua, Wang, Zhe, Mao, Bingyu, Tan, Ninghua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6539016/ https://www.ncbi.nlm.nih.gov/pubmed/31083642 http://dx.doi.org/10.3390/molecules24091829 |
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