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Diclofenac-Derived Hybrids for Treatment of Actinic Keratosis and Squamous Cell Carcinoma

In this work, hybrid compounds 1–4 obtained by conjugation of the non-steroidal anti-inflammatory drug diclofenac, with natural molecules endowed with antioxidant and antiproliferative activity were prepared. The antiproliferative activity of these hybrids was evaluated on immortalized human keratin...

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Detalles Bibliográficos
Autores principales: Tampucci, Silvia, Carpi, Sara, Digiacomo, Maria, Polini, Beatrice, Fogli, Stefano, Burgalassi, Susi, Macchia, Marco, Nieri, Paola, Manera, Clementina, Monti, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6539072/
https://www.ncbi.nlm.nih.gov/pubmed/31075867
http://dx.doi.org/10.3390/molecules24091793