The Study of the Aggregated Pattern of TX100 Micelle by Using Solvent Paramagnetic Relaxation Enhancements

TX100 (Triton X-100) is a typical nonionic surfactant that is widely used in biology. However, the detailed aggregated conformation of TX100, such as the boundary between the polar region and the nonpolar region, and the arrangement of hydrophobic chains in micelles, are still controversial. In the...

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Autores principales: Zhang, Liang, Chai, Xin, Sun, Peng, Yuan, Bin, Jiang, Bin, Zhang, Xu, Liu, Maili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6539090/
https://www.ncbi.nlm.nih.gov/pubmed/31027389
http://dx.doi.org/10.3390/molecules24091649
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author Zhang, Liang
Chai, Xin
Sun, Peng
Yuan, Bin
Jiang, Bin
Zhang, Xu
Liu, Maili
author_facet Zhang, Liang
Chai, Xin
Sun, Peng
Yuan, Bin
Jiang, Bin
Zhang, Xu
Liu, Maili
author_sort Zhang, Liang
collection PubMed
description TX100 (Triton X-100) is a typical nonionic surfactant that is widely used in biology. However, the detailed aggregated conformation of TX100, such as the boundary between the polar region and the nonpolar region, and the arrangement of hydrophobic chains in micelles, are still controversial. In the manuscript, the aggregation pattern of TX100 has been studied using sPREs (solvent Paramagnetic Relaxation Enhancements)-based NMR (Nuclear Magnetic Resonance spectroscopy). It was found that the average positions of the protons in the TX100 micelle are consistent with those in the multilayer staggered spherical micelle model with the p-tertoctylphenyl groups dispersing in the different layers.
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spelling pubmed-65390902019-05-31 The Study of the Aggregated Pattern of TX100 Micelle by Using Solvent Paramagnetic Relaxation Enhancements Zhang, Liang Chai, Xin Sun, Peng Yuan, Bin Jiang, Bin Zhang, Xu Liu, Maili Molecules Article TX100 (Triton X-100) is a typical nonionic surfactant that is widely used in biology. However, the detailed aggregated conformation of TX100, such as the boundary between the polar region and the nonpolar region, and the arrangement of hydrophobic chains in micelles, are still controversial. In the manuscript, the aggregation pattern of TX100 has been studied using sPREs (solvent Paramagnetic Relaxation Enhancements)-based NMR (Nuclear Magnetic Resonance spectroscopy). It was found that the average positions of the protons in the TX100 micelle are consistent with those in the multilayer staggered spherical micelle model with the p-tertoctylphenyl groups dispersing in the different layers. MDPI 2019-04-26 /pmc/articles/PMC6539090/ /pubmed/31027389 http://dx.doi.org/10.3390/molecules24091649 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Zhang, Liang
Chai, Xin
Sun, Peng
Yuan, Bin
Jiang, Bin
Zhang, Xu
Liu, Maili
The Study of the Aggregated Pattern of TX100 Micelle by Using Solvent Paramagnetic Relaxation Enhancements
title The Study of the Aggregated Pattern of TX100 Micelle by Using Solvent Paramagnetic Relaxation Enhancements
title_full The Study of the Aggregated Pattern of TX100 Micelle by Using Solvent Paramagnetic Relaxation Enhancements
title_fullStr The Study of the Aggregated Pattern of TX100 Micelle by Using Solvent Paramagnetic Relaxation Enhancements
title_full_unstemmed The Study of the Aggregated Pattern of TX100 Micelle by Using Solvent Paramagnetic Relaxation Enhancements
title_short The Study of the Aggregated Pattern of TX100 Micelle by Using Solvent Paramagnetic Relaxation Enhancements
title_sort study of the aggregated pattern of tx100 micelle by using solvent paramagnetic relaxation enhancements
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6539090/
https://www.ncbi.nlm.nih.gov/pubmed/31027389
http://dx.doi.org/10.3390/molecules24091649
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