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Silybin-Induced Apoptosis Occurs in Parallel to the Increase of Ceramides Synthesis and miRNAs Secretion in Human Hepatocarcinoma Cells
Silybin is a flavonolignan extracted from Silybum marianum (milk thistle) with hepatoprotective, antioxidant, and anti-inflammatory activity. Several studies have shown that silybin is highly effective to prevent and treat different types of cancer and that its antitumor mechanisms involve the arres...
Autores principales: | Zappavigna, Silvia, Vanacore, Daniela, Lama, Stefania, Potenza, Nicoletta, Russo, Aniello, Ferranti, Pasquale, Dallio, Marcello, Federico, Alessandro, Loguercio, Carmelina, Sperlongano, Pasquale, Caraglia, Michele, Stiuso, Paola |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6539179/ https://www.ncbi.nlm.nih.gov/pubmed/31058823 http://dx.doi.org/10.3390/ijms20092190 |
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