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Unappreciated Role of LDHA and LDHB to Control Apoptosis and Autophagy in Tumor Cells
Tumor cells possess a high metabolic plasticity, which drives them to switch on the anaerobic glycolysis and lactate production when challenged by hypoxia. Among the enzymes mediating this plasticity through bidirectional conversion of pyruvate and lactate, the lactate dehydrogenase A (LDHA) and lac...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6539221/ https://www.ncbi.nlm.nih.gov/pubmed/31035592 http://dx.doi.org/10.3390/ijms20092085 |