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Targeting Caspase 8: Using Structural and Ligand-Based Approaches to Identify Potential Leads for the Treatment of Multi-Neurodegenerative Diseases

Caspase 8 is a central player in the apoptotic cell death pathway and is also essential for cytokine processing. The critical role of this protease in cell death pathways has generated research interest because its activation has also been linked with neural cell death. Thus, blocking the activity o...

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Detalles Bibliográficos
Autores principales: Ahmad, Khurshid, Balaramnavar, Vishal M., Chaturvedi, Navaneet, Khan, Saif, Haque, Shafiul, Lee, Yong-Ho, Choi, Inho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6539313/
https://www.ncbi.nlm.nih.gov/pubmed/31083628
http://dx.doi.org/10.3390/molecules24091827