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Structure/Activity Analysis of TASK-3 Channel Antagonists Based on a 5,6,7,8 tetrahydropyrido[4,3-d]pyrimidine

TASK-3 potassium (K(+)) channels are highly expressed in the central nervous system, regulating the membrane potential of excitable cells. TASK-3 is involved in neurotransmitter action and has been identified as an oncogenic K(+) channel. For this reason, the understanding of the action mechanism of...

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Detalles Bibliográficos
Autores principales:	Ramírez, David, Bedoya, Mauricio, Kiper, Aytug K., Rinné, Susanne, Morales-Navarro, Samuel, Hernández-Rodríguez, Erix W., Sepúlveda, Francisco V., Decher, Niels, González, Wendy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6539479/ https://www.ncbi.nlm.nih.gov/pubmed/31067753 http://dx.doi.org/10.3390/ijms20092252

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