Anti-Cancer Activity of Novel Dihydrotestosterone-Derived Ring A-Condensed Pyrazoles on Androgen Non-Responsive Prostate Cancer Cell Lines

Regioselective synthesis of novel ring A-fused arylpyrazoles of dihydrotestosterone (DHT) was carried out in two steps under facile reaction conditions. Aldol condensation of DHT with acetaldehyde afforded a 2-ethylidene derivative regio- and stereo-selectively, which was reacted with different aryl...

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Detalles Bibliográficos
Autores principales: Mótyán, Gergő, Gopisetty, Mohana Krishna, Kiss-Faludy, Réka Eleonóra, Kulmány, Ágnes, Zupkó, István, Frank, Éva, Kiricsi, Mónika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6539495/
https://www.ncbi.nlm.nih.gov/pubmed/31052484
http://dx.doi.org/10.3390/ijms20092170

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6539495/
https://www.ncbi.nlm.nih.gov/pubmed/31052484
http://dx.doi.org/10.3390/ijms20092170

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