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Anti-Cancer Activity of Novel Dihydrotestosterone-Derived Ring A-Condensed Pyrazoles on Androgen Non-Responsive Prostate Cancer Cell Lines

Regioselective synthesis of novel ring A-fused arylpyrazoles of dihydrotestosterone (DHT) was carried out in two steps under facile reaction conditions. Aldol condensation of DHT with acetaldehyde afforded a 2-ethylidene derivative regio- and stereo-selectively, which was reacted with different aryl...

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Detalles Bibliográficos
Autores principales:	Mótyán, Gergő, Gopisetty, Mohana Krishna, Kiss-Faludy, Réka Eleonóra, Kulmány, Ágnes, Zupkó, István, Frank, Éva, Kiricsi, Mónika
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6539495/ https://www.ncbi.nlm.nih.gov/pubmed/31052484 http://dx.doi.org/10.3390/ijms20092170

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