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High Molecular Weight Hyaluronan Suppresses Macrophage M1 Polarization and Enhances IL-10 Production in PM(2.5)-Induced Lung Inflammation

PM(2.5) is particulate matter with a diameter of 2.5 μm or less. Airway macrophages are the key players regulating PM(2.5)-induced inflammation. High molecular weight hyaluronan (HMW-HA) has previously been shown to exert protective effects on PM(2.5)-induced acute lung injury and inflammation. Howe...

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Detalles Bibliográficos
Autores principales: Shi, Qiwen, Zhao, Lan, Xu, Chenming, Zhang, Leifang, Zhao, Hang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6539614/
https://www.ncbi.nlm.nih.gov/pubmed/31067702
http://dx.doi.org/10.3390/molecules24091766