Citrate-Induced p85α–PTEN Complex Formation Causes G(2)/M Phase Arrest in Human Pharyngeal Squamous Carcinoma Cell Lines

Citrate is a key intermediate of the tricarboxylic acid cycle and acts as an allosteric signal to regulate the production of cellular ATP. An elevated cytosolic citrate concentration inhibits growth in several types of human cancer cells; however, the underlying mechanism by which citrate induces th...

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Detalles Bibliográficos
Autores principales: Hung, Kuang-Chen, Wang, Shyang-Guang, Lin, Meng-Liang, Chen, Shih-Shun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6539620/
https://www.ncbi.nlm.nih.gov/pubmed/31035650
http://dx.doi.org/10.3390/ijms20092105

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6539620/
https://www.ncbi.nlm.nih.gov/pubmed/31035650
http://dx.doi.org/10.3390/ijms20092105

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