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Citrate-Induced p85α–PTEN Complex Formation Causes G(2)/M Phase Arrest in Human Pharyngeal Squamous Carcinoma Cell Lines
Citrate is a key intermediate of the tricarboxylic acid cycle and acts as an allosteric signal to regulate the production of cellular ATP. An elevated cytosolic citrate concentration inhibits growth in several types of human cancer cells; however, the underlying mechanism by which citrate induces th...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6539620/ https://www.ncbi.nlm.nih.gov/pubmed/31035650 http://dx.doi.org/10.3390/ijms20092105 |