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Application of Acyzol in the Context of Zinc Deficiency and Perspectives

Zinc is one of the most important essential trace elements. It is involved in more than 300 enzyme systems and is an indispensable participant in many biochemical processes. Zinc deficiency causes a number of disorders in the human body, the main ones being the delay of growth and puberty, immune di...

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Autores principales: Aliev, Gjumrakch, Li, Yi, Chubarev, Vladimir N., Lebedeva, Svetlana A., Parshina, Lidiya N., Trofimov, Boris A., Sologova, Susanna S., Makhmutova, Alfiya, Avila-Rodriguez, Marco F., Klochkov, Sergey G., Galenko-Yaroshevsky, Pavel A., Tarasov, Vadim V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6539662/
https://www.ncbi.nlm.nih.gov/pubmed/31035445
http://dx.doi.org/10.3390/ijms20092104
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author Aliev, Gjumrakch
Li, Yi
Chubarev, Vladimir N.
Lebedeva, Svetlana A.
Parshina, Lidiya N.
Trofimov, Boris A.
Sologova, Susanna S.
Makhmutova, Alfiya
Avila-Rodriguez, Marco F.
Klochkov, Sergey G.
Galenko-Yaroshevsky, Pavel A.
Tarasov, Vadim V.
author_facet Aliev, Gjumrakch
Li, Yi
Chubarev, Vladimir N.
Lebedeva, Svetlana A.
Parshina, Lidiya N.
Trofimov, Boris A.
Sologova, Susanna S.
Makhmutova, Alfiya
Avila-Rodriguez, Marco F.
Klochkov, Sergey G.
Galenko-Yaroshevsky, Pavel A.
Tarasov, Vadim V.
author_sort Aliev, Gjumrakch
collection PubMed
description Zinc is one of the most important essential trace elements. It is involved in more than 300 enzyme systems and is an indispensable participant in many biochemical processes. Zinc deficiency causes a number of disorders in the human body, the main ones being the delay of growth and puberty, immune disorders, and cognitive dysfunctions. There are over two billion people in the world suffering from zinc deficiency conditions. Acyzol, a zinc-containing medicine, developed as an antidote against carbon monoxide poisoning, demonstrates a wide range of pharmacological activities: Anti-inflammatory, reparative, detoxifying, immunomodulatory, bacteriostatic, hepatoprotective, adaptogenic, antioxidant, antihypoxic, and cardioprotective. The presence of zinc in the composition of Acyzol suggests the potential of the drug in the treatment and prevention of zinc deficiency conditions, such as Prasad’s disease, immune system pathology, alopecia, allergodermatoses, prostate dysfunction, psoriasis, stomatitis, periodontitis, and delayed mental and physical development in children. Currently, the efficiency of Acyzol in the cases of zinc deficiency is shown in a large number of experimental studies. So, Acyzol can be used as a highly effective drug for pharmacologic therapy of a wide range of diseases and conditions and it opens up new perspectives in the treatment and prevention of zinc deficiency conditions.
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spelling pubmed-65396622019-06-04 Application of Acyzol in the Context of Zinc Deficiency and Perspectives Aliev, Gjumrakch Li, Yi Chubarev, Vladimir N. Lebedeva, Svetlana A. Parshina, Lidiya N. Trofimov, Boris A. Sologova, Susanna S. Makhmutova, Alfiya Avila-Rodriguez, Marco F. Klochkov, Sergey G. Galenko-Yaroshevsky, Pavel A. Tarasov, Vadim V. Int J Mol Sci Review Zinc is one of the most important essential trace elements. It is involved in more than 300 enzyme systems and is an indispensable participant in many biochemical processes. Zinc deficiency causes a number of disorders in the human body, the main ones being the delay of growth and puberty, immune disorders, and cognitive dysfunctions. There are over two billion people in the world suffering from zinc deficiency conditions. Acyzol, a zinc-containing medicine, developed as an antidote against carbon monoxide poisoning, demonstrates a wide range of pharmacological activities: Anti-inflammatory, reparative, detoxifying, immunomodulatory, bacteriostatic, hepatoprotective, adaptogenic, antioxidant, antihypoxic, and cardioprotective. The presence of zinc in the composition of Acyzol suggests the potential of the drug in the treatment and prevention of zinc deficiency conditions, such as Prasad’s disease, immune system pathology, alopecia, allergodermatoses, prostate dysfunction, psoriasis, stomatitis, periodontitis, and delayed mental and physical development in children. Currently, the efficiency of Acyzol in the cases of zinc deficiency is shown in a large number of experimental studies. So, Acyzol can be used as a highly effective drug for pharmacologic therapy of a wide range of diseases and conditions and it opens up new perspectives in the treatment and prevention of zinc deficiency conditions. MDPI 2019-04-29 /pmc/articles/PMC6539662/ /pubmed/31035445 http://dx.doi.org/10.3390/ijms20092104 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Aliev, Gjumrakch
Li, Yi
Chubarev, Vladimir N.
Lebedeva, Svetlana A.
Parshina, Lidiya N.
Trofimov, Boris A.
Sologova, Susanna S.
Makhmutova, Alfiya
Avila-Rodriguez, Marco F.
Klochkov, Sergey G.
Galenko-Yaroshevsky, Pavel A.
Tarasov, Vadim V.
Application of Acyzol in the Context of Zinc Deficiency and Perspectives
title Application of Acyzol in the Context of Zinc Deficiency and Perspectives
title_full Application of Acyzol in the Context of Zinc Deficiency and Perspectives
title_fullStr Application of Acyzol in the Context of Zinc Deficiency and Perspectives
title_full_unstemmed Application of Acyzol in the Context of Zinc Deficiency and Perspectives
title_short Application of Acyzol in the Context of Zinc Deficiency and Perspectives
title_sort application of acyzol in the context of zinc deficiency and perspectives
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6539662/
https://www.ncbi.nlm.nih.gov/pubmed/31035445
http://dx.doi.org/10.3390/ijms20092104
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