Cargando…

EZH2 inhibition suppresses bladder cancer cell growth and metastasis via the JAK2/STAT3 signaling pathway

The aim of the current study was to investigate the role of enhancer of zeste 2 polycomb repressive complex 2 subunit (EZH2) in the progression of bladder cancer. Human bladder cancer tissue samples were analyzed by immunohistochemistry, and the association between the clinicopathological parameters...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Zhiyuan, Du, Yang, Liu, Xiuheng, Chen, Hui, Weng, Xiaodong, Guo, Jia, Wang, Min, Wang, Xiao, Wang, Lei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2019
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6539677/ https://www.ncbi.nlm.nih.gov/pubmed/31289569 http://dx.doi.org/10.3892/ol.2019.10359

Ejemplares similares

Inhibition of BRD4 suppresses tumor growth in prostate cancer via the enhancement of FOXO1 expression
por: Tan, Yifan, et al.
Publicado: (2018)

Energy-Stress-Mediated AMPK Activation Promotes GPX4-Dependent Ferroptosis through the JAK2/STAT3/P53 Axis in Renal Cancer
por: Li, Yanze, et al.
Publicado: (2022)

Tanshinone I inhibits the growth and metastasis of osteosarcoma via suppressing JAK/STAT3 signalling pathway
por: Wang, Weiguo, et al.
Publicado: (2019)

Hispidulin suppresses cell growth and metastasis by targeting PIM1 through JAK2/STAT3 signaling in colorectal cancer
por: Liu, Kaili, et al.
Publicado: (2018)

USP21 promotes cell proliferation and metastasis through suppressing EZH2 ubiquitination in bladder carcinoma
por: Chen, Yong, et al.
Publicado: (2017)

MicroRNA-144 Suppresses Prostate Cancer Growth and Metastasis by Targeting EZH2
por: Sun, Xin-bo, et al.
Publicado: (2021)

Liensinine Inhibits Osteosarcoma Growth by ROS-Mediated Suppression of the JAK2/STAT3 Signaling Pathway
por: Jia, Fei, et al.
Publicado: (2022)

Anlotinib combined with temozolomide suppresses glioblastoma growth via mediation of JAK2/STAT3 signaling pathway
por: Xu, Peng, et al.
Publicado: (2022)

Modified completely intrafascial radical cysprostatectomy for bladder cancer: a single-center, blinded, controlled study
por: Wang, Xiao, et al.
Publicado: (2021)

Honokiol inhibits bladder tumor growth by suppressing EZH2/miR-143 axis
por: Zhang, Qing, et al.
Publicado: (2015)

Effects of apigenin on the expression levels of B-cell lymphoma-2, Fas and Fas ligand in renal ischemia-reperfusion injury in rats
por: Liu, Yang, et al.
Publicado: (2017)

MicroRNA-448 suppresses metastasis of pancreatic ductal adenocarcinoma through targeting JAK1/STAT3 pathway
por: Yu, Dan-Li, et al.
Publicado: (2022)

Ozone therapy could attenuate tubulointerstitial injury in adenine-induced CKD rats by mediating Nrf2 and NF-κB
por: Yu, Gang, et al.
Publicado: (2016)

Ginsenoside Rh4 Suppressed Metastasis of Lung Adenocarcinoma via Inhibiting JAK2/STAT3 Signaling
por: Zhang, Yan, et al.
Publicado: (2022)

Ginkgetin induces apoptosis in 786-O cell line via suppression of JAK2-STAT3 pathway
por: Ren, Yu, et al.
Publicado: (2016)

RCAN1.4 attenuates renal fibrosis through inhibiting calcineurin-mediated nuclear translocation of NFAT2
por: Zhang, Jianjian, et al.
Publicado: (2021)

CBX2 and EZH2 cooperatively promote the growth and metastasis of lung adenocarcinoma
por: Hu, Fei-Fei, et al.
Publicado: (2021)

Progranulin promoted the proliferation, metastasis, and suppressed apoptosis via JAK2-STAT3/4 signaling pathway in papillary thyroid carcinoma
por: Dong, Yanxu, et al.
Publicado: (2023)

Hwanggeumchal sorghum Induces Cell Cycle Arrest, and Suppresses Tumor Growth and Metastasis through Jak2/STAT Pathways in Breast Cancer Xenografts
por: Park, Jin Hee, et al.
Publicado: (2012)

Pharmacologic down-regulation of EZH2 suppresses bladder cancer in vitro and in vivo
por: Tang, Shou-Hung, et al.
Publicado: (2014)

Resveratrol Loaded by Folate-Modified Liposomes Inhibits Osteosarcoma Growth and Lung Metastasis via Regulating JAK2/STAT3 Pathway
por: Zhu, Wen Ting, et al.
Publicado: (2023)

Ischemic postconditioning inhibits apoptosis in an in vitro proximal tubular cell model
por: WENG, XIAODONG, et al.
Publicado: (2015)

ML264 inhibits osteosarcoma growth and metastasis via inhibition of JAK2/STAT3 and WNT/β‐catenin signalling pathways
por: Huang, Hai, et al.
Publicado: (2020)

STAT3-Induced Upregulation of lncRNA CASC9 Promotes the Progression of Bladder Cancer by Interacting with EZH2 and Affecting the Expression of PTEN
por: Yuan, Bo, et al.
Publicado: (2020)

CCL18-NIR1 promotes oral cancer cell growth and metastasis by activating the JAK2/STAT3 signaling pathway
por: Jiang, Xiao, et al.
Publicado: (2020)

Icaritin suppresses multiple myeloma, by inhibiting IL-6/JAK2/STAT3
por: Zhu, Shicong, et al.
Publicado: (2015)

Resveratrol inhibits TNF-α-induced inflammation to protect against renal ischemia/reperfusion injury in diabetic rats
por: Wang, Min, et al.
Publicado: (2020)

Dihydroartemisinin as a Putative STAT3 Inhibitor, Suppresses the Growth of Head and Neck Squamous Cell Carcinoma by Targeting Jak2/STAT3 Signaling
por: Jia, Lifeng, et al.
Publicado: (2016)

Immunosuppressive effect of bladder cancer on function of dendritic cells involving of Jak2/STAT3 pathway
por: Xiu, Weigang, et al.
Publicado: (2016)

Inhibition of Brd4 alleviates renal ischemia/reperfusion injury-induced apoptosis and endoplasmic reticulum stress by blocking FoxO4-mediated oxidative stress
por: Liu, Hao, et al.
Publicado: (2019)

Suppression of autophagy through JAK2/STAT3 contributes to the therapeutic action of rhynchophylline on asthma
por: Li, Hui, et al.
Publicado: (2021)

Downregulation of lysine-specific demethylase 1 enhances the sensitivity of hormone-sensitive prostate cancer cells to androgen deprivation therapy
por: Wang, Min, et al.
Publicado: (2021)

Dihydrotanshinone Inhibits Hepatocellular Carcinoma by Suppressing the JAK2/STAT3 Pathway
por: Hu, Xue, et al.
Publicado: (2021)

Salidroside suppresses the growth and invasion of human osteosarcoma cell lines MG63 and U2OS in vitro by inhibiting the JAK2/STAT3 signaling pathway
por: Huang, Lintuo, et al.
Publicado: (2019)

Loss of ZIP facilitates JAK2-STAT3 activation in tamoxifen-resistant breast cancer
por: Zhu, Ning, et al.
Publicado: (2020)

Chrysoeriol suppresses hyperproliferation of rheumatoid arthritis fibroblast-like synoviocytes and inhibits JAK2/STAT3 signaling
por: Wu, Jia-Ying, et al.
Publicado: (2022)

LNK promotes the growth and metastasis of triple negative breast cancer via activating JAK/STAT3 and ERK1/2 pathway
por: Lv, Jianxin, et al.
Publicado: (2020)

MiR-32 Inhibits Proliferation and Metastasis by Targeting EZH2 in Glioma
por: Zhang, Yuan, et al.
Publicado: (2019)

Effect of picroside II on apoptosis induced by renal ischemia/reperfusion injury in rats
por: WANG, LEI, et al.
Publicado: (2015)

Osteosarcoma cell proliferation suppression via SHP-2-mediated inactivation of the JAK/STAT3 pathway by tubocapsenolide A
por: Zhu, Dongrong, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_f2v809vog1lbltnt2s7421qdtv