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Enhancement of Binding Affinity of Folate to Its Receptor by Peptide Conjugation

(1) Background: The folate receptor (FR) is a target for cancer treatment and detection. Expression of the FR is restricted in normal cells but overexpressed in many types of tumors. Folate was conjugated with peptides for enhancing binding affinity to the FR. (2) Materials and Methods: For conjugat...

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Detalles Bibliográficos
Autores principales:	Dharmatti, Roopa, Miyatake, Hideyuki, Nandakumar, Avanashiappan, Ueda, Motoki, Kobayashi, Kenya, Kiga, Daisuke, Yamamura, Masayuki, Ito, Yoshihiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6539678/ https://www.ncbi.nlm.nih.gov/pubmed/31052315 http://dx.doi.org/10.3390/ijms20092152

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