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Induction of t(11;14) IgH enhancer/promoter-cyclin D1 gene translocation using CRISPR/Cas9

Chromosomal translocation is a key process in the oncogenic transformation of somatic cells. Previously, artificial induction of chromosomal translocation was performed using homologous recombination-mediated loxP labeling of target regions followed by Cre-mediated recombination. Recent progress in...

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Detalles Bibliográficos
Autores principales:	Tsuyama, Naohiro, Abe, Yu, Yanagi, Aki, Yanai, Yukari, Sugai, Misaki, Katafuchi, Atsushi, Kawamura, Fumihiko, Kamiya, Kenji, Sakai, Akira
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2019
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6539856/ https://www.ncbi.nlm.nih.gov/pubmed/31289497 http://dx.doi.org/10.3892/ol.2019.10303

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