Cargando…

Autophagy-Related Proteins GABARAP and LC3B Label Structures of Similar Size but Different Shape in Super-Resolution Imaging

Subcellular structures containing autophagy-related proteins of the Atg8 protein family have been investigated with conventional wide-field fluorescence and single molecule localisation microscopy. Fusion proteins of GABARAP and LC3B, respectively, with EYFP were overexpressed in HEK293 cells. While...

Descripción completa

Detalles Bibliográficos
Autores principales:	Abdollahzadeh, Iman, Hendriks, Johnny, Sanwald, Julia L., Simons, Indra M., Hoffmann, Silke, Weiergräber, Oliver H., Willbold, Dieter, Gensch, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6539863/ https://www.ncbi.nlm.nih.gov/pubmed/31086037 http://dx.doi.org/10.3390/molecules24091833

Ejemplares similares

Deficiency of GABARAP but Not Its Paralogs Causes Enhanced EGF-Induced EGFR Degradation
por: Dobner, Jochen, et al.
Publicado: (2020)

The GABARAP Co-Secretome Identified by APEX2-GABARAP Proximity Labelling of Extracellular Vesicles
por: Sanwald, Julia L., et al.
Publicado: (2020)

Lack of GABARAP-Type Proteins Is Accompanied by Altered Golgi Morphology and Surfaceome Composition
por: Sanwald, Julia L., et al.
Publicado: (2020)

The highly GABARAP specific rat monoclonal antibody 8H5 visualizes GABARAP in immunofluorescence imaging at endogenous levels
por: Simons, Indra M., et al.
Publicado: (2019)

Author Correction: The highly GABARAP specific rat monoclonal antibody 8H5 visualizes GABARAP in immunofluorescence imaging at endogenous levels
por: Simons, Indra M., et al.
Publicado: (2019)

The Atg8 Family of Proteins—Modulating Shape and Functionality of Autophagic Membranes
por: Abdollahzadeh, Iman, et al.
Publicado: (2017)

Centriolar Satellites Control GABARAP Ubiquitination and GABARAP-Mediated Autophagy
por: Joachim, Justin, et al.
Publicado: (2017)

No ATG8s, no problem? How LC3/GABARAP proteins contribute to autophagy
por: Martens, Sascha
Publicado: (2016)

Direct binding to GABARAP family members is essential for HIV-1 Nef plasma membrane localization
por: Boeske, Alexandra, et al.
Publicado: (2017)

MAPK15/ERK8 stimulates autophagy by interacting with LC3 and GABARAP proteins
por: Colecchia, David, et al.
Publicado: (2012)

Redundancy of human ATG4 protease isoforms in autophagy and LC3/GABARAP processing revealed in cells
por: Agrotis, Alexander, et al.
Publicado: (2019)

The Machado–Joseph disease deubiquitylase ataxin‐3 interacts with LC3C/GABARAP and promotes autophagy
por: Herzog, Laura K., et al.
Publicado: (2019)

Enrichment of GABARAP Relative to LC3 in the Axonal Initial Segments of Neurons
por: Koike, Masato, et al.
Publicado: (2013)

A short isoform of ATG7 fails to lipidate LC3/GABARAP
por: Ogmundsdottir, M. H., et al.
Publicado: (2018)

Lipidation of the LC3/GABARAP family of autophagy proteins relies upon a membrane curvature-sensing domain in Atg3
por: Nath, Sangeeta, et al.
Publicado: (2014)

Human ATG4 autophagy proteases counteract attachment of ubiquitin-like LC3/GABARAP proteins to other cellular proteins
por: Agrotis, Alexander, et al.
Publicado: (2019)

Solution structure of the autophagy-related protein LC3C reveals a polyproline II motif on a mobile tether with phosphorylation site
por: Krichel, Carsten, et al.
Publicado: (2019)

LGG-1/GABARAP lipidation is not required for autophagy and development in Caenorhabditis elegans
por: Leboutet, Romane, et al.
Publicado: (2023)

LC3/GABARAPs drive ubiquitin-independent recruitment of Optineurin and NDP52 to amplify mitophagy
por: Padman, Benjamin Scott, et al.
Publicado: (2019)

Publisher Correction: A short isoform of ATG7 fails to lipidate LC3/GABARAP
por: Ogmundsdottir, M. H., et al.
Publicado: (2018)

Development of GABARAP family protein-sensitive LIR-based probes for neuronal autophagy
por: Jeon, Pureum, et al.
Publicado: (2019)

SNSMIL, a real-time single molecule identification and localization algorithm for super-resolution fluorescence microscopy
por: Tang, Yunqing, et al.
Publicado: (2015)

Monitoring LC3- or GABARAP-positive autophagic membranes using modified RavZ-based probes
por: Park, Sang-Won, et al.
Publicado: (2019)

A Conserved LIR Motif in Connexins Mediates Ubiquitin-Independent Binding to LC3/GABARAP Proteins
por: Catarino, Steve, et al.
Publicado: (2020)

Tumor suppression in mice lacking GABARAP, an Atg8/LC3 family member implicated in autophagy, is associated with alterations in cytokine secretion and cell death
por: Salah, F S, et al.
Publicado: (2016)

NEAT1 Confers Radioresistance to Hepatocellular Carcinoma Cells by Inducing Autophagy through GABARAP
por: Sakaguchi, Hiromi, et al.
Publicado: (2022)

Apolipoprotein L9 interacts with LC3/GABARAP and is a microtubule-associated protein with a widespread subcellular distribution
por: Thekkinghat, Arvind A., et al.
Publicado: (2019)

Activation of ULK Kinase and Autophagy by GABARAP Trafficking from the Centrosome Is Regulated by WAC and GM130
por: Joachim, Justin, et al.
Publicado: (2015)

The crystal structure of the FAM134B–GABARAP complex provides mechanistic insights into the selective binding of FAM134 to the GABARAP subfamily
por: Zhao, Junfeng, et al.
Publicado: (2021)

TBK1‐mediated phosphorylation of LC3C and GABARAP‐L2 controls autophagosome shedding by ATG4 protease
por: Herhaus, Lina, et al.
Publicado: (2019)

GABARAPs dysfunction by autophagy deficiency in adolescent brain impairs GABA(A) receptor trafficking and social behavior
por: Hui, Kelvin K., et al.
Publicado: (2019)

Effect of ATG12–ATG5-ATG16L1 autophagy E3-like complex on the ability of LC3/GABARAP proteins to induce vesicle tethering and fusion
por: Iriondo, Marina N., et al.
Publicado: (2023)

Structural and functional analysis of the GABARAP interaction motif (GIM)
por: Rogov, Vladimir V, et al.
Publicado: (2017)

Prediction of GABARAP interaction with the GABA type A receptor
por: Irwin, B.W.J., et al.
Publicado: (2018)

Atg8 family LC3/GABARAP proteins are crucial for autophagosome–lysosome fusion but not autophagosome formation during PINK1/Parkin mitophagy and starvation
por: Nguyen, Thanh Ngoc, et al.
Publicado: (2016)

Members of the autophagy class III phosphatidylinositol 3-kinase complex I interact with GABARAP and GABARAPL1 via LIR motifs
por: Birgisdottir, Åsa Birna, et al.
Publicado: (2019)

In silico inhibition of GABARAP activity using antiepileptic medicinal derived compounds
por: Mathew, Shilu, et al.
Publicado: (2015)

Focused Design of Novel Cyclic Peptides Endowed with GABARAP-Inhibiting Activity
por: Fassi, Enrico Mario Alessandro, et al.
Publicado: (2022)

GABARAP ameliorates IL-1β-induced inflammatory responses and osteogenic differentiation in bone marrow-derived stromal cells by activating autophagy
por: Guo, Xiaobo, et al.
Publicado: (2021)

Growth-rate dependency of ribosome abundance and translation elongation rate in Corynebacterium glutamicum differs from that in Escherichia coli
por: Matamouros, Susana, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_iga21um531r6cgghdfnmgmjoht