Optical Resolution of Rimantadine

This work discloses a new procedure for the resolution of commercially available racemic rimantadine hydrochloride to enantiomerically pure (S)-rimantadine using (R)-phenoxypropionic acid as a recyclable resolving reagent. Good chemical yields, operational ease, and low-cost structure underscore the...

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Detalles Bibliográficos
Autores principales: Han, Jianlin, Takeda, Ryosuke, Sato, Tatsunori, Moriwaki, Hiroki, Abe, Hidenori, Izawa, Kunisuke, Soloshonok, Vadim A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6539882/
https://www.ncbi.nlm.nih.gov/pubmed/31083636
http://dx.doi.org/10.3390/molecules24091828

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6539882/
https://www.ncbi.nlm.nih.gov/pubmed/31083636
http://dx.doi.org/10.3390/molecules24091828

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