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An Innovative Ultrasonic Apparatus and Technology for Diagnosis of Freeze-Drying Process

The freeze-drying process removes water from a product through freezing, sublimation and desorption procedures. However, the extreme conditions of the freeze-drying environment, such as the limited space, vacuum and freezing temperatures of as much as −50 °C, may block the ability to use certain dia...

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Autores principales: Cheng, Chin-Chi, Tseng, Yen-Hsiang, Huang, Shih-Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6539970/
https://www.ncbi.nlm.nih.gov/pubmed/31083500
http://dx.doi.org/10.3390/s19092181
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author Cheng, Chin-Chi
Tseng, Yen-Hsiang
Huang, Shih-Chang
author_facet Cheng, Chin-Chi
Tseng, Yen-Hsiang
Huang, Shih-Chang
author_sort Cheng, Chin-Chi
collection PubMed
description The freeze-drying process removes water from a product through freezing, sublimation and desorption procedures. However, the extreme conditions of the freeze-drying environment, such as the limited space, vacuum and freezing temperatures of as much as −50 °C, may block the ability to use certain diagnostic sensors. In this paper, an ultrasonic transducer (UT) is integrated onto the bottom of a specially designed frozen bottle for the purpose of observing the freeze-drying process of water at varying amounts. The temperatures and visual observations made with a camera are then compared with the corresponding ultrasonic signatures. Among all of the diagnostic tools and technologies available, only ultrasonic and visual records are able to analyze the entire progression of the freeze-drying process of water. Compared with typical experiment settings, the indication of drying point for water by the amplitude variations of ultrasonic L(3) echo could reduce the process period and energy consumption. This study demonstrates how an innovative frozen bottle, an integrated ultrasonic sensor and diagnostic methods used to measure and optimize the freeze-drying process of water can save energy.
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spelling pubmed-65399702019-06-04 An Innovative Ultrasonic Apparatus and Technology for Diagnosis of Freeze-Drying Process Cheng, Chin-Chi Tseng, Yen-Hsiang Huang, Shih-Chang Sensors (Basel) Article The freeze-drying process removes water from a product through freezing, sublimation and desorption procedures. However, the extreme conditions of the freeze-drying environment, such as the limited space, vacuum and freezing temperatures of as much as −50 °C, may block the ability to use certain diagnostic sensors. In this paper, an ultrasonic transducer (UT) is integrated onto the bottom of a specially designed frozen bottle for the purpose of observing the freeze-drying process of water at varying amounts. The temperatures and visual observations made with a camera are then compared with the corresponding ultrasonic signatures. Among all of the diagnostic tools and technologies available, only ultrasonic and visual records are able to analyze the entire progression of the freeze-drying process of water. Compared with typical experiment settings, the indication of drying point for water by the amplitude variations of ultrasonic L(3) echo could reduce the process period and energy consumption. This study demonstrates how an innovative frozen bottle, an integrated ultrasonic sensor and diagnostic methods used to measure and optimize the freeze-drying process of water can save energy. MDPI 2019-05-11 /pmc/articles/PMC6539970/ /pubmed/31083500 http://dx.doi.org/10.3390/s19092181 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Cheng, Chin-Chi
Tseng, Yen-Hsiang
Huang, Shih-Chang
An Innovative Ultrasonic Apparatus and Technology for Diagnosis of Freeze-Drying Process
title An Innovative Ultrasonic Apparatus and Technology for Diagnosis of Freeze-Drying Process
title_full An Innovative Ultrasonic Apparatus and Technology for Diagnosis of Freeze-Drying Process
title_fullStr An Innovative Ultrasonic Apparatus and Technology for Diagnosis of Freeze-Drying Process
title_full_unstemmed An Innovative Ultrasonic Apparatus and Technology for Diagnosis of Freeze-Drying Process
title_short An Innovative Ultrasonic Apparatus and Technology for Diagnosis of Freeze-Drying Process
title_sort innovative ultrasonic apparatus and technology for diagnosis of freeze-drying process
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6539970/
https://www.ncbi.nlm.nih.gov/pubmed/31083500
http://dx.doi.org/10.3390/s19092181
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