Hepatotoxicity of a Cannabidiol-Rich Cannabis Extract in the Mouse Model

The goal of this study was to investigate Cannabidiol (CBD) hepatotoxicity in 8-week-old male B6C3F(1) mice. Animals were gavaged with either 0, 246, 738, or 2460 mg/kg of CBD (acute toxicity, 24 h) or with daily doses of 0, 61.5, 184.5, or 615 mg/kg for 10 days (sub-acute toxicity). These doses wer...

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Detalles Bibliográficos
Autores principales: Ewing, Laura E., Skinner, Charles M., Quick, Charles M., Kennon-McGill, Stefanie, McGill, Mitchell R., Walker, Larry A., ElSohly, Mahmoud A., Gurley, Bill J., Koturbash, Igor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6539990/
https://www.ncbi.nlm.nih.gov/pubmed/31052254
http://dx.doi.org/10.3390/molecules24091694

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6539990/
https://www.ncbi.nlm.nih.gov/pubmed/31052254
http://dx.doi.org/10.3390/molecules24091694

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