Cargando…

Computational Aminoacyl-tRNA Synthetase Library Design for Photocaged Tyrosine

Engineering aminoacyl-tRNA synthetases (aaRSs) provides access to the ribosomal incorporation of noncanonical amino acids via genetic code expansion. Conventional targeted mutagenesis libraries with 5–7 positions randomized cover only marginal fractions of the vast sequence space formed by up to 30...

Descripción completa

Detalles Bibliográficos
Autores principales:	Baumann, Tobias, Hauf, Matthias, Richter, Florian, Albers, Suki, Möglich, Andreas, Ignatova, Zoya, Budisa, Nediljko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6539999/ https://www.ncbi.nlm.nih.gov/pubmed/31083552 http://dx.doi.org/10.3390/ijms20092343

Ejemplares similares

Expanding the Scope of Orthogonal Translation with Pyrrolysyl-tRNA Synthetases Dedicated to Aromatic Amino Acids
por: Tseng, Hsueh-Wei, et al.
Publicado: (2020)

Efficient Unnatural Protein Production by Pyrrolysyl-tRNA Synthetase With Genetically Fused Solubility Tags
por: Koch, Nikolaj G., et al.
Publicado: (2021)

Aminoacyl-tRNA synthetases
por: Rubio Gomez, Miguel Angel, et al.
Publicado: (2020)

Peculiarities of aminoacyl-tRNA synthetases from trypanosomatids
por: Parrot, Camila, et al.
Publicado: (2021)

Aminoacyl-tRNA Synthetases: On Anti-Synthetase Syndrome and Beyond
por: Galindo-Feria, Angeles S., et al.
Publicado: (2022)

Plasticity and Constraints of tRNA Aminoacylation Define Directed Evolution of Aminoacyl-tRNA Synthetases
por: Crnković, Ana, et al.
Publicado: (2019)

Aminoacyl-tRNA synthetases in medicine and disease
por: Yao, Peng, et al.
Publicado: (2013)

Aminoacyl-tRNA Synthetase Complexes in Evolution
por: Havrylenko, Svitlana, et al.
Publicado: (2015)

The aminoacyl-tRNA synthetases of Drosophila melanogaster
por: Lu, Jiongming, et al.
Publicado: (2016)

Regulation of Angiogenesis by Aminoacyl-tRNA Synthetases
por: Mirando, Adam C., et al.
Publicado: (2014)

Characterization of Aminoacyl-tRNA Synthetases in Chromerids
por: Sharaf, Abdoallah, et al.
Publicado: (2019)

Roles of Aminoacyl-tRNA Synthetases in Cancer
por: Zhou, Zheng, et al.
Publicado: (2020)

Aminoacyl-tRNA synthetases of the multi-tRNA synthetase complex and their role in tumorigenesis
por: Khan, Krishnendu, et al.
Publicado: (2022)

Expanding a tyrosyl-tRNA synthetase assay to other aminoacyl-tRNA synthetases
por: Richardson, Charles J., et al.
Publicado: (2015)

Common Peptides Study of Aminoacyl-tRNA Synthetases
por: Gottlieb, Assaf, et al.
Publicado: (2011)

In Silico Discovery of Aminoacyl-tRNA Synthetase Inhibitors
por: Zhao, Yaxue, et al.
Publicado: (2014)

The Mitochondrial Aminoacyl tRNA Synthetases: Genes and Syndromes
por: Diodato, Daria, et al.
Publicado: (2014)

Continuous directed evolution of aminoacyl-tRNA synthetases
por: Bryson, David I., et al.
Publicado: (2017)

The complex evolutionary history of aminoacyl-tRNA synthetases
por: Chaliotis, Anargyros, et al.
Publicado: (2017)

Aminoacyl-tRNA synthetases in human health and disease
por: Turvey, Alexandra K., et al.
Publicado: (2022)

Editorial: Noncanonical functions of Aminoacyl-tRNA synthetases
por: Sun, Litao, et al.
Publicado: (2023)

Engineering Pyrrolysyl-tRNA Synthetase for the Incorporation of Non-Canonical Amino Acids with Smaller Side Chains
por: Koch, Nikolaj G., et al.
Publicado: (2021)

Aminoacyl-tRNA synthetases as drug targets in eukaryotic parasites()
por: Pham, James S., et al.
Publicado: (2013)

Aminoacyl-tRNA synthetase evolution and sectoring of the genetic code
por: Pak, Daewoo, et al.
Publicado: (2018)

Localization and RNA Binding of Mitochondrial Aminoacyl tRNA Synthetases
por: Garin, Shahar, et al.
Publicado: (2020)

Aminoacyl-tRNA synthetases, therapeutic targets for infectious diseases
por: Lee, Eun-Young, et al.
Publicado: (2018)

Aminoacyl-tRNA synthetase deficiencies in search of common themes
por: Fuchs, Sabine A., et al.
Publicado: (2018)

The regulatory roles of aminoacyl-tRNA synthetase in cardiovascular disease
por: Zou, Yulin, et al.
Publicado: (2021)

Natural Trojan horse inhibitors of aminoacyl-tRNA synthetases
por: Travin, Dmitrii Y., et al.
Publicado: (2021)

Functional and pathologic association of aminoacyl-tRNA synthetases with cancer
por: Sung, Yulseung, et al.
Publicado: (2022)

Evolution of Life on Earth: tRNA, Aminoacyl-tRNA Synthetases and the Genetic Code
por: Lei, Lei, et al.
Publicado: (2020)

RNA granule-clustered mitochondrial aminoacyl-tRNA synthetases form multiple complexes with the potential to fine-tune tRNA aminoacylation
por: Peng, Gui-Xin, et al.
Publicado: (2022)

Prediction and classification of aminoacyl tRNA synthetases using PROSITE domains
por: Panwar, Bharat, et al.
Publicado: (2010)

Dual Organellar Targeting of Aminoacyl-tRNA Synthetases in Diatoms and Cryptophytes
por: Gile, Gillian H., et al.
Publicado: (2015)

The Roles of Compensatory Evolution and Constraint in Aminoacyl tRNA Synthetase Evolution
por: Adrion, Jeffrey R., et al.
Publicado: (2016)

Aminoacyl tRNA synthetases and their relationships with peripheral nerve degeneration and regeneration
por: Jung, Junyang
Publicado: (2015)

Multi-Omics Database Analysis of Aminoacyl-tRNA Synthetases in Cancer
por: Wang, Justin, et al.
Publicado: (2020)

Roles of aminoacyl-tRNA synthetases in immune regulation and immune diseases
por: Nie, Anzheng, et al.
Publicado: (2019)

Aminoacyl-tRNA Synthetases as Valuable Targets for Antimicrobial Drug Discovery
por: Pang, Luping, et al.
Publicado: (2021)

The Evolutionary Fate of Mitochondrial Aminoacyl-tRNA Synthetases in Amitochondrial Organisms
por: Igloi, Gabor L.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_qaff7olevkkk7ue3aqce0af41d